Evidence map›Paper›PMID 34739484›Full record

ArticlePloS one2021

Regular testing of asymptomatic healthcare workers identifies cost-efficient SARS-CoV-2 preventive measures.

Daniel Sanchez-Taltavull, Violeta Castelo-Szekely, Shaira Murugan, Jonathan I D Hamley, Tim Rollenske, Stephanie C Ganal-Vonarburg, Isabel Büchi, Adrian Keogh, Hai Li, Lilian Salm and 7 more

Abstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Daniel Sanchez-TaltavullDepartment of Visceral Surgery and Medicine, Bern University Hospital, University of Bern, Bern, Switzerland.ORCID 0000-0002-4944-0360
Violeta Castelo-SzekelyDepartment of Visceral Surgery and Medicine, Bern University Hospital, University of Bern, Bern, Switzerland.
Shaira MuruganDepartment of Visceral Surgery and Medicine, Bern University Hospital, University of Bern, Bern, Switzerland.
Jonathan I D HamleyDepartment of Visceral Surgery and Medicine, Bern University Hospital, University of Bern, Bern, Switzerland.ORCID 0000-0001-5755-2867
Tim RollenskeDepartment of Visceral Surgery and Medicine, Bern University Hospital, University of Bern, Bern, Switzerland.
Stephanie C Ganal-VonarburgDepartment of Visceral Surgery and Medicine, Bern University Hospital, University of Bern, Bern, Switzerland.
Isabel BüchiDepartment of Visceral Surgery and Medicine, Bern University Hospital, University of Bern, Bern, Switzerland.
Adrian KeoghDepartment of Visceral Surgery and Medicine, Bern University Hospital, University of Bern, Bern, Switzerland.
Hai LiDepartment of Visceral Surgery and Medicine, Bern University Hospital, University of Bern, Bern, Switzerland.
Lilian SalmDepartment of Visceral Surgery and Medicine, Bern University Hospital, University of Bern, Bern, Switzerland.
Daniel SpariDepartment of Visceral Surgery and Medicine, Bern University Hospital, University of Bern, Bern, Switzerland.
Bahtiyar YilmazDepartment of Visceral Surgery and Medicine, Bern University Hospital, University of Bern, Bern, Switzerland.ORCID 0000-0003-1888-9226
Jakob ZimmermannDepartment of Visceral Surgery and Medicine, Bern University Hospital, University of Bern, Bern, Switzerland.
Michael GerfinDepartment of Economics, University of Bern, Bern, Switzerland.
Edgar RoldanICTP, The Abdus Salam International Centre for Theoretical Physics, Trieste, Italy.
Guido BeldiDepartment of Visceral Surgery and Medicine, Bern University Hospital, University of Bern, Bern, Switzerland.
UVCM-COVID researchers

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protecting healthcare professionals is crucial in maintaining a functioning healthcare system. The risk of infection and optimal preventive strategies for healthcare workers during the COVID-19 pandemic remain poorly understood. Here we report the results of a cohort study that included pre- and asymptomatic healthcare workers. A weekly testing regime has been performed in this cohort since the beginning of the COVID-19 pandemic to identify infected healthcare workers. Based on these observations we have developed a mathematical model of SARS-CoV-2 transmission that integrates the sources of infection from inside and outside the hospital. The data were used to study how regular testing and a desynchronisation protocol are effective in preventing transmission of COVID-19 infection at work, and compared both strategies in terms of workforce availability and cost-effectiveness. We showed that case incidence among healthcare workers is higher than would be explained solely by community infection. Furthermore, while testing and desynchronisation protocols are both effective in preventing nosocomial transmission, regular testing maintains work productivity with implementation costs.

Indexed as

Asymptomatic InfectionsHealth PersonnelSARS-CoV-2AlgorithmsCost-Benefit AnalysisCOVID-19COVID-19 TestingCross InfectionData CollectionDelivery of Health CareHospitalsHumansMass ScreeningModels, TheoreticalOccupational ExposurePandemics

Identifiers

PMID34739484
PMCPMC8570514

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.