Evidence map›Paper›PMID 34739467›Full record

ArticleActa bio-medica : Atenei Parmensis2021

COVID-19: an outbreak in a nursing home in spring 2021.

Silvana Castaldi, Stefano Zani, Alessia Lai, Gianguglielmo Zehender, Annalisa Bergna, Catia Rossana Boriello, Danilo Cereda

Abstract read
In one paragraph

Article in Acta bio-medica : Atenei Parmensis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Silvana CastaldiUniversità degli Studi di Milano. silvana.castaldi@unimi.it.
Stefano ZaniDepartment of Biomedical and Clinical Sciences L. Sacco, University of Milan, Italy. zanistefano77@gmail.com.
Alessia LaiDepartment of Biomedical and Clinical Sciences L. Sacco, University of Milan, Italy. alessia.lai@unimi.it.
Gianguglielmo ZehenderDepartment of Biomedical and Clinical Sciences L. Sacco, University of Milan, Italy. gianguglielmo.zehender@unimi.it.
Annalisa BergnaDepartment of Biomedical and Clinical Sciences L. Sacco, University of Milan, Italy. annalisa.bergna@unimi.it.
Catia Rossana BorielloASST FBF e Sacco, Milan, Italy. 'catia_rosanna_borriello@regione.lombardia.it.
Danilo CeredaUO Prevenzione Regione Lombardia, Italy. danilo_cereda@regione.lombardia.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionNursing home residents were the most vulnerable population to be affected by Coronavirus disease 2019 (COVID-19) in Italy. The Italian vaccination strategy decided to indicate them as the target population in the first phase of the massive vaccination campaign. We carried out an analysis on an outbreak of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection which occurred in a nursing home in northern Italy (Cremona) after the administration of the complete vaccination cycle affecting most of the guests of the structure.

methodsData relating to the outbreak were obtained through the Regional Surveillance System for Infectious Diseases of Lombardia Region.

resultsDuring the outbreak, among the 61 guests, 56 were vaccinated. Thirty four were found positive for COVID-19: 22 were asymptomatic, 12 were symptomatic and 4 died. The observed difference in the number of deaths between vaccinated and non-vaccinated subjects was significant. During the outbreak 104 healthcare workers (HCWs) were employed in the nursing home, only 66 were vaccinated. Eight HCWs were found COVID-19 positive, 4 of them were vaccinated and of female gender.

conclusionsSimilarly to data reported in literature for described outbreaks, we observed that the vaccine is able to protect from the symptomatic form and a valid antibody response protect from a symptomatic disease. The low number of HCWs found positive indicates a correct use of individual protective devices.

Indexed as

COVID-19Disease OutbreaksFemaleHealth PersonnelHumansNursing HomesSARS-CoV-2

Identifiers

PMID34739467
PMCPMC8851026

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.