ArticleActa bio-medica : Atenei Parmensis2021
An assessment of case-fatality and infection-fatality rates of first and second COVID-19 waves in Italy.
Article in Acta bio-medica : Atenei Parmensis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Suicidality and/or Death-Related Thoughts in Health Workers After Pandemics: The Role of DYMERS.Journal of clinical medicine · 2025Article
- The influence of meteorological factors on COVID-19 spread in Italy during the first and second wave.Environmental research · 2023Article
- A deep learning approach for Spatio-Temporal forecasting of new cases and new hospital admissions of COVID-19 spread in Reggio Emilia, Northern Italy.Journal of biomedical informatics · 2022Article
- Seroprevalence Survey of Anti-SARS-CoV-2 Antibodies in a Population of Emilia-Romagna Region, Northern Italy.International journal of environmental research and public health · 2022Article
- Emergency Medical Services Calls Analysis for Trend Prediction during Epidemic Outbreaks: Interrupted Time Series Analysis on 2020-2021 COVID-19 Epidemic in Lazio, Italy.International journal of environmental research and public health · 2022Article
- Revising the legislation of Ethics Committees to ease biomedical research in humans across the world: lessons from the COVID-19 emergency.Acta bio-medica : Atenei Parmensis · 2022Article
- Italian National Recovery and Resilience Plan: a Healthcare Renaissance after the COVID-19 crisis?Acta bio-medica : Atenei Parmensis · 2021Article
- The association between first and second wave COVID-19 mortality in Italy.BMC public health · 2021Article
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6 authors.
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Abstract
BACKGROUND AND
aimThe exact COVID-19 severity is still not well defined and it is hotly debated due to the a few methodological issues such as the uncertainties about the spread of the SARS-CoV-2 infection.
methodsWe investigated COVID-19 case-fatality rate and infection-fatality rate in 2020 in Italy, a country severely affected by the pandemic, basing our assessment on publicly available data, and calculating such measures during the first and second waves.
resultsWe found that province-specific crude case-fatality rate in the first wave (February-July 2020) had a median value of 12.0%. Data about infection-fatality rate was more difficult to compute, due to large underestimation of SARS-CoV-2 infection during the first wave when asymptomatic individuals were very rarely tested. However, when using as a reference population-based seroprevalence data for anti-SARS-CoV-2 antibodies collected in May-July 2020, we computed an infection-fatality rate of 2.2%. During the second wave (Sep-Dec 2020), when SARS-CoV-2 testing was greatly increased and extended to many asymptomatic individuals, we could only compute a 'hybrid' case/infection-fatality rate with a value of 2.2%, similar to the infection-fatality rate of the first wave.
conclusionsOverall, this study allowed to assess the COVID-19 case- and infection-fatality rates in Italy before of variant spread and vaccine availability, confirming their high values compared with other airborne infections like influenza. Our findings for Italy were similar to those characterizing other Western European countries.
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