Evidence map›Paper›PMID 34739453›Full record

SynthesisActa bio-medica : Atenei Parmensis2021

Epidemiological assessment of the first COVID-19 epidemic wave in Lombardy. A systematic review.

Carlo Signorelli, Anna Odone, Vincenza Gianfredi, Federica Balzarini, Daria Bucci, Roberto Croci, Giovanni Gaetti, Giuseppe Stirparo, Ranieri Guerra

Abstract readSystematic Review
In one paragraph

Synthesis in Acta bio-medica : Atenei Parmensis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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  4. Changing the stroke network during pandemic scenarios does not affect the management of patients with a positive Cincinnati prehospital stroke scale.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Carlo SignorelliSchool of Medicine, Vita-Salute San Raffaele University, Via Olgettina, 58, 20132 Milan, Italy. signorelli.carlo@hsr.it.
Anna OdoneDepartment of Public Health, Experimental and Forensic Medicine, University of Pavia, 27100 Pavia, Italy. anna.odone@unipv.it.
Vincenza GianfrediSchool of Public Health, Vita-Salute San Raffaele University, Milan, Italy; CAPHRI Care and Public Health Research Institute, Maastricht University, Maastricht, the Netherlands. gianfredi.vincenza@hsr.it.
Federica BalzariniDipartimento per la Programmazione, Accreditamento, Acquisto delle Prestazioni Sanitarie e Sociosanitarie (P.A.A.P.S.S.), Servizio Autorizzazione e Accreditamento, Agenzia di Tutela della Salute (ATS) di Bergamo, Via Galliccioli, 4, 24121 Bergamo, Italy. federica.balzarini@gmail.com.
Daria BucciSchool of Medicine, Vita-Salute San Raffaele University, Via Olgettina, 58, 20132 Milan, Italy. bucci.daria@hsr.it.
Roberto CrociSchool of Medicine, Vita-Salute San Raffaele University, Via Olgettina, 58, 20132 Milan, Italy. croci.roberto@hsr.it.
Giovanni GaettiSchool of Medicine, Vita-Salute San Raffaele University, Via Olgettina, 58, 20132 Milan, Italy. gaetti.giovanni@hsr.it.
Giuseppe StirparoSchool of Medicine, Vita-Salute San Raffaele University, Via Olgettina, 58, 20132 Milan, Italy. stirparo.giuseppe@hsr.it.
Ranieri GuerraWorld Health Organization, Geneva, Switzerland. guerrar@who.int.

Funding

World Health Organization 001
6 · The paper itself

Abstract

BACKGROUND AND

aimAfter the first cases of COVID-19 detected in Wuhan (China), the virus rapidly spread in the world, so much so that on February 20 the first autochthonous case was officially identified in Italy. However, this person had no apparent history of travel abroad or contact with people tested positive for the virus. For this reason, the aim of this literature review was to reconstruct the epidemiological dynamics of the first wave of SARS-CoV-2 infection in the Lombardy Region.

methodsTo this end, a systematic review was carried out on PubMed/MEDLINE and EMBASE, and on grey literature. All article assessing incidence, mortality and hospitalizations by Lombardy province and municipality, and the impact of the main containment and organizational measures were considered eligible. In addition, data on general mortality and mortality due to COVID-19, hospital admission, and serological and environmental were also retrieved.

resultsFrom the included studies, it emerged that Lombardy was the first European region in which the virus began to circulate as early as January 2020 (and probably even earlier). Despite the high number of cases and deaths recorded, the reproduction number observed in Lombardy Region was, at the beginning of March 2020, the same (or lower) than in other regions.

conclusionsIn conclusion, data of the first epidemic wave in Lombardy, compared to other Italian and foreign regions, highlight the extreme criticality of having had the first autochthonous case (and the first substantial outbreaks) when knowledge was still scarce and individual prevention measures were not widespread.

Indexed as

COVID-19EpidemicsDisease OutbreaksHumansIncidenceItalySARS-CoV-2

Identifiers

PMID34739453
PMCPMC8851015

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.