ArticleScience advances2021
Positive interactions are common among culturable bacteria.
Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 125 papers, 1 of them a synthesis that pooled it.
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Who cites it
125 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Coexistence Theory for Microbial Ecology, and Vice Versa.Environmental microbiology · 2025Pooled it
- Low Levels of Amino Acid Auxotrophy Among Environmental Pseudomonas Isolates.Environmental microbiology · 2026Article
- Obligate cross-feeding of metabolites is common in soil microbial communities.Nature microbiology · 2026Article
- Article
- Increased nutrient diversity can induce loss of microbial diversity through enhanced resource uptake.Nature ecology & evolution · 2026Article
- Polychip-A High-Throughput Droplet Microfluidics Platform for Interrogating Microbial Interactions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Biofilm-mediated antibiotic cross-protection:Microbiology spectrum · 2026Article
- Quartet: Disentangling positive and negative components of microbial interactions.PLoS computational biology · 2026Article
- Functional and ecological drivers of bacterial interactions in glacier-fed stream biofilms.mSystems · 2026Article
- Article
- Bacterial proteome foundation model enhances functional prediction from enzymes to ecological interactions.bioRxiv : the preprint server for biology · 2026Article
- Microbial Interactions Shape Spatial Organisation and Transcriptional Responses in a Model Mixed-Species Biofilm.Microbial ecology · 2026Article
- Emergent coexistence and the limits of reductionism in ecological communities.PLoS computational biology · 2026Article
- Iron limitation promotes metabolic cross-feeding between cheese ripening bacteria.The ISME journal · 2026Article
- Hypersensitivity of chitin degradation to initial species densities due to monomer diffusion.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Linking complex microbial interactions and dysbiosis through a disordered Lotka-Volterra model.eLife · 2026Article
- Deciphering microbial interactions using a label-free microbead sorting approach.ISME communications · 2026Article
- Potential contribution of microbial interaction to stochasticity of microbiota assembly.ISME communications · 2026Article
- Quenching corrinoid-based interactions in a model bacterial coculture.ISME communications · 2026Article
- Bottleneck size drives the evolution of cooperative traits in an aggregative multicellular myxobacterium.PLoS biology · 2026Article
65 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Interspecies interactions shape the structure and function of microbial communities. In particular, positive, growth-promoting interactions can substantially affect the diversity and productivity of natural and engineered communities. However, the prevalence of positive interactions and the conditions in which they occur are not well understood. To address this knowledge gap, we used kChip, an ultrahigh-throughput coculture platform, to measure 180,408 interactions among 20 soil bacteria across 40 carbon environments. We find that positive interactions, often described to be rare, occur commonly and primarily as parasitisms between strains that differ in their carbon consumption profiles. Notably, nongrowing strains are almost always promoted by strongly growing strains (85%), suggesting a simple positive interaction–mediated approach for cultivation, microbiome engineering, and microbial consortium design.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.