ArticleScience advances2021
Modulating the pro-apoptotic activity of cytochrome c at a biomimetic electrified interface.
Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Gold Nanocluster-Promoted Interfacial Electron Transfer of Cytochrome c at an Aqueous-Organic Interface.Nano letters · 2025Article
- Specifically Breaking Through the Injured Blood-Brain Barrier With Tannic Acid-Based Nanomedicine for Ischemic Stroke Ischemia Reperfusion Treatment.Exploration (Beijing, China) · 2025Article
- Proton Tunneling Allows a Proton-Coupled Electron Transfer Process in the Cancer Cell.JACS Au · 2024Article
- Potential-Modulated Surface-Enhanced Raman Spectroscopy of Tolmetin at Gold Nanoparticle Film Functionalized Polarizable Liquid-Liquid Interfaces.The journal of physical chemistry. C, Nanomaterials and interfaces · 2024Article
- Nanocatalytic NO gas therapy against orthotopic oral squamous cell carcinoma by single iron atomic nanocatalysts.Science and technology of advanced materials · 2024Article
- Potential-Modulated Ion Distributions in the Back-to-Back Electrical Double Layers at a Polarised Liquid|Liquid Interface Regulate the Kinetics of Interfacial Electron Transfer.ChemElectroChem · 2023Article
- On the origin of chaotrope-modulated electrocatalytic activity of cytochromeChemical communications (Cambridge, England) · 2022Article
- Electrogeneration of a Free-Standing Cytochrome c-Silica Matrix at a Soft Electrified Interface.Langmuir : the ACS journal of surfaces and colloids · 2021Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Programmed cell death via apoptosis is a natural defence against excessive cell division, crucial for fetal development to maintenance of homeostasis and elimination of precancerous and senescent cells. Here, we demonstrate an electrified liquid biointerface that replicates the molecular machinery of the inner mitochondrial membrane at the onset of apoptosis. By mimicking in vivo cytochrome c (Cyt c) interactions with cell membranes, our platform allows us to modulate the conformational plasticity of the protein by simply varying the electrochemical environment at an aqueous-organic interface. We observe interfacial electron transfer between an organic electron donor decamethylferrocene and O
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Registered trials
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