Evidence map›Paper›PMID 34739308›Full record

ArticleScience advances2021

Two interacting transcriptional coactivators cooperatively control plant immune responses.

Huan Chen, Min Li, Guang Qi, Ming Zhao, Longyu Liu, Jingyi Zhang, Gongyou Chen, Daowen Wang, Fengquan Liu, Zheng Qing Fu

Abstract read
In one paragraph

Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
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  5. Article
  6. Plant NLRs are getting into higher-order architectures.The Plant journal : for cell and molecular biology · 2026
    Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. International journal of molecular sciences · 2025
    Article
  14. A virulent milRNA ofHorticulture research · 2025
    Article
  15. Article
  16. Novel Insight into the Prevention and Therapeutic Treatment ofInternational journal of molecular sciences · 2024
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Huan ChenInstitute of Plant Protection, Jiangsu Academy of Agricultural Sciences, Jiangsu Key Laboratory for Food Quality and Safety-State Key Laboratory Cultivation Base of Ministry of Science and Technology, Nanjing 210014, China.ORCID 0000-0003-1182-3144
Min LiDepartment of Biological Sciences, University of South Carolina, Columbia, SC 29208, USA.
Guang QiDepartment of Biological Sciences, University of South Carolina, Columbia, SC 29208, USA.
Ming ZhaoDepartment of Biological Sciences, University of South Carolina, Columbia, SC 29208, USA.
Longyu LiuDepartment of Biological Sciences, University of South Carolina, Columbia, SC 29208, USA.
Jingyi ZhangInstitute of Plant Protection, Jiangsu Academy of Agricultural Sciences, Jiangsu Key Laboratory for Food Quality and Safety-State Key Laboratory Cultivation Base of Ministry of Science and Technology, Nanjing 210014, China.
Gongyou ChenSchool of Agriculture and Biology/State Key Laboratory of Microbial Metabolism, Shanghai Jiao Tong University, Shanghai 200240, China.ORCID 0000-0003-1979-2880
Daowen WangState Key Laboratory of Wheat and Maize Crop Science and College of Agronomy, Henan Agricultural University, Zhengzhou 450002, China.ORCID 0000-0002-6230-8735
Fengquan LiuInstitute of Plant Protection, Jiangsu Academy of Agricultural Sciences, Jiangsu Key Laboratory for Food Quality and Safety-State Key Laboratory Cultivation Base of Ministry of Science and Technology, Nanjing 210014, China.ORCID 0000-0001-9325-1500
Zheng Qing FuDepartment of Biological Sciences, University of South Carolina, Columbia, SC 29208, USA.ORCID 0000-0003-1519-6192

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The phytohormone salicylic acid (SA) plays a pivotal role in plant defense against biotrophic and hemibiotrophic pathogens. NPR1 and EDS1 function as two central hubs in plant local and systemic immunity. However, it is unclear how NPR1 orchestrates gene regulation and whether EDS1 directly participates in transcriptional reprogramming. Here, we show that NPR1 and EDS1 synergistically activate

Identifiers

PMID34739308
PMCPMC8570602

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.