ReviewHippocampus2021
Imaging human engrams using 7 Tesla magnetic resonance imaging.
Review in Hippocampus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 14 citations in OpenAlex.
- Exploring anterior thalamus functional connectivity with cortical regions in prospective memory with ultra-high-field functional MRI.Brain communications · 2025Article
- Hippocampal subfields and their neocortical interactions during autobiographical memory.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Article
- The effect of loss incentives on prospective memory in healthy older adults: study protocol of a randomized controlled trial using ultra-high field fMRI.BMC psychiatry · 2023Article
- Cardiovascular Brain Circuits.Circulation research · 2023Review
- The future of integrative neuroscience: The big questions.Frontiers in integrative neuroscience · 2023Article
- Imaging human engrams using 7 Tesla magnetic resonance imaging.Hippocampus · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The investigation of the physical traces of memories (engrams) has made significant progress in the last decade due to optogenetics and fluorescent cell tagging applied in rodents. Engram cells were identified. The ablation of engram cells led to the loss of the associated memory, silent memories were reactivated, and artificial memories were implanted in the brain. Human engram research lags behind engram research in rodents due to methodological and ethical constraints. However, advances in multivariate analysis techniques of functional magnetic resonance imaging (fMRI) data and machine learning algorithms allowed the identification of stable engram patterns in humans. In addition, MRI scanners with an ultrahigh field strength of 7 Tesla (T) have left their prototype state and became more common around the world to assist human engram research. Although most engram research in humans is still being performed with a field strength of 3T, fMRI at 7T will push engram research. Here, we summarize the current state and findings of human engram research and discuss the advantages and disadvantages of applying 7 versus 3T fMRI to image human memory traces.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.