Evidence map›Paper›PMID 34739171›Full record

ArticleOral diseases2022

Virucidal activity in vitro of mouthwashes against a feline coronavirus type II.

Alessio Buonavoglia, Michele Camero, Gianvito Lanave, Cristiana Catella, Claudia Maria Trombetta, Maria Giovanna Gandolfi, Gerardo Palazzo, Vito Martella, Carlo Prati

Abstract read
In one paragraph

Article in Oral diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alessio BuonavogliaDental School, Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy.
Michele CameroDepartment of Veterinary Medicine, University of Bari, Valenzano, Italy.
Gianvito LanaveDepartment of Veterinary Medicine, University of Bari, Valenzano, Italy.ORCID https://orcid.org/0000-0003-4614-677X
Cristiana CatellaDepartment of Veterinary Medicine, University of Bari, Valenzano, Italy.
Claudia Maria TrombettaDepartment of Molecular and Developmental Medicine, University of Siena, Siena, Italy.
Maria Giovanna GandolfiDental School, Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy.
Gerardo PalazzoDepartment of Chemistry, and CSGI (Center for Colloid and Surface Science), University of Bari, Bari, Italy.
Vito MartellaDepartment of Veterinary Medicine, University of Bari, Valenzano, Italy.
Carlo PratiDental School, Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can occur through saliva and aerosol droplets deriving from the upper aerodigestive tract during coughing, sneezing, talking, and even during oral inspection or dental procedures. The aim of this study was to assess in vitro virucidal activity of commercial and experimental mouthwashes against a feline coronavirus (FCoV) strain. Commercial and experimental (commercial-based products with addition of either sodium dodecyl sulfate (SDS) or thymus vulgaris essential oil (TEO) at different concentrations) mouthwashes were placed in contact with FCoV for different time intervals, that is, 30 s (T30), 60 s (T60), and 180 s (T180); subsequently, the virus was titrated on Crandell Reese Feline Kidney cells. An SDS-based commercial mouthwash reduced the viral load by 5 log10 tissue culture infectious dose (TCID)

Indexed as

Coronavirus, FelineCOVID-19AnimalsCatsCetylpyridiniumMouthwashesSARS-CoV-2CetylpyridiniumMouthwashesdental practicefeline coronavirusin vitromouthwashesvirucidal activity

Identifiers

PMID34739171
PMCPMC9788155

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.