ArticleeLife2021
The hepatic AMPK-TET1-SIRT1 axis regulates glucose homeostasis.
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In one paragraph
Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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0cells of the map it votes in
22citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
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Who cites it
22 citing papers in PubMed, 27 citations in OpenAlex.
- Glucose-responsive AMPK-TET2-5hmc oscillation links metabolic stress to circadian transcription and Parkinson's disease relevance.NPJ Parkinson's disease · 2026Article
- Molecular signaling effects of electrical stimulation of the soleus muscle during 6 days of dry immersion.Sports medicine and health science · 2026Article
- Sirtuin 1 as an emerging exerkine in the aging process: unveiling its multifaceted biological roles.Biogerontology · 2026Review
- Electroacupuncture activates the TET1/PPARα pathway to protect mitochondrial function in MASLD.Journal of inflammation (London, England) · 2026Article
- Effects of AMPK/PGC-1α on gluconeogenesis in skeletal muscle of animals under overwintering starvation and its molecular mechanism: review.Animal bioscience · 2026Article
- Activating protein kinases to treat diseases: Current understanding and future challenges.Acta pharmaceutica Sinica. B · 2026Review
- Protein acetylation in atherosclerosis: beyond inflammation to core cellular processes and therapeutic potential.Frontiers in immunology · 2026Review
- TET1 loss propels the development of hyperthyroidism by remodeling histone modifications of PAX8 promoter.Experimental & molecular medicine · 2025Article
- TET1: The epigenetic architect of clinical disease progression.Genes & diseases · 2025Review
- MOTS-c-modified functional self-assembly peptide hydrogels enhance the activity of nucleus pulposus-derived mesenchymal stem cells of intervertebral disc degeneration.Materials today. Bio · 2025Article
- Liver TET1 promotes metabolic dysfunction-associated steatotic liver disease.EMBO molecular medicine · 2025Article
- Giant panda seasonal adaptations in feeding strategies and blood physiology.Frontiers in veterinary science · 2025Article
- Exploring histone deacetylases in type 2 diabetes mellitus: pathophysiological insights and therapeutic avenues.Clinical epigenetics · 2024Review
- Post-Translational Modifications and Diabetes.Biomolecules · 2024Review
- Selective androgen receptor modulator use and related adverse events including drug-induced liver injury: Analysis of suspected cases.European journal of clinical pharmacology · 2024Review
- MiR-29b Alleviates High Glucose-induced Inflammation and Apoptosis in Podocytes by Down-regulating PRKAB2.Endocrine, metabolic & immune disorders drug targets · 2024Article
- Glucose promotes cell growth and casein synthesis via ATF4/Nrf2-Sestrin2- AMPK-mTORC1 pathway in dairy cow mammary epithelial cells.Animal biotechnology · 2023Article
- Vascular Endothelial Growth Factor A (VEGFA) Regulates Hepatic Lipid and Glycogen Metabolism inInternational journal of molecular sciences · 2023Article
- SIRT1 activation promotes energy homeostasis and reprograms liver cancer metabolism.Journal of translational medicine · 2023Article
- TET (Ten-eleven translocation) family proteins: structure, biological functions and applications.Signal transduction and targeted therapy · 2023Review
Corrections and comments
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Authors and funding
24 authors at 5 institutions in 1 country.
Chunbo Zhang *Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases of Ministry of Education, Gannan Medical University, Ganzhou, China.ORCID https://orcid.org/0000-0001-9618-9415
Tianyu Zhong *Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases of Ministry of Education, Gannan Medical University, Ganzhou, China.
Yuanyuan Li *Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, China.
Xianfeng Li *Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, China.
Xiaopeng YuanSchool of Pharmacy, Nanchang University, Nanchang, China.
Linlin LiuPrecision Medicine Center, First Affiliated Hospital of Gannan Medical University, Ganzhou, China.
Weilin WuKey Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases of Ministry of Education, Gannan Medical University, Ganzhou, China.
Jing WuKey Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases of Ministry of Education, Gannan Medical University, Ganzhou, China.
Ye WuSchool of Pharmacy, Nanchang University, Nanchang, China.
Rui LiangState Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Biology, School of Life Sciences, Xiamen University, Xiamen, China.
Xinhua XieKey Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases of Ministry of Education, Gannan Medical University, Ganzhou, China.
Chuanchuan KangPrecision Medicine Center, First Affiliated Hospital of Gannan Medical University, Ganzhou, China.
Yuwen LiuKey Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases of Ministry of Education, Gannan Medical University, Ganzhou, China.
Zhonghong LaiKey Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases of Ministry of Education, Gannan Medical University, Ganzhou, China.
Jianbo XiaoKey Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases of Ministry of Education, Gannan Medical University, Ganzhou, China.
Zhixian TangPrecision Medicine Center, First Affiliated Hospital of Gannan Medical University, Ganzhou, China.
Riqun JinPrecision Medicine Center, First Affiliated Hospital of Gannan Medical University, Ganzhou, China.
Yan WangBeijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, China.
Yongwei XiaoKey Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases of Ministry of Education, Gannan Medical University, Ganzhou, China.
Jin ZhangSchool of Basic Medical Sciences, Nanchang University, Nanchang, China.
Jian LiState Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Biology, School of Life Sciences, Xiamen University, Xiamen, China.
Qian LiuKey Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases of Ministry of Education, Gannan Medical University, Ganzhou, China.
Zhongsheng SunBeijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, China.
Jianing ZhongKey Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases of Ministry of Education, Gannan Medical University, Ganzhou, China.ORCID https://orcid.org/0000-0002-2781-3437
Gannan Medical University · CNChinese Academy of Sciences · CNFirst Affiliated Hospital of Gannan Medical University · CNNanchang University · CNXiamen University · CN
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ten-eleven translocation methylcytosine dioxygenase 1 (TET1) is involved in multiple biological functions in cell development, differentiation, and transcriptional regulation.
Indexed as
AMP-Activated Protein KinasesAnimalsDNA-Binding ProteinsFastingGene Expression RegulationGluconeogenesisHomeostasisHypoglycemic AgentsLiverMetforminMiceMice, TransgenicProto-Oncogene ProteinsSirtuin 1Transcription FactorsAMP-Activated Protein KinasesDNA-Binding ProteinsHypoglycemic AgentsMetforminProto-Oncogene ProteinsSirtuin 1TET1 protein, mouseTranscription Factorsacetylation modificationbiochemistrychemical biologyglucose metabolismmedicinemouseSIRT1TET1transcriptional regulation
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.