Evidence map›Paper›PMID 34738600›Full record

ArticleActa bio-medica : Atenei Parmensis2021

Correlation of Serum Decoy Receptor 3 and Interleukin-6 with Severity of Coronary Artery Diseases in Male Acute Myocardial Infarction Patients.

Hossein Doustkami, Leli Avesta, Behzad Babapour, Mohammad Hossein Boskabady, Ali Nikoukhesal, Mohammad Reza Aslani

Open access · greenAbstract read
In one paragraph

Article in Acta bio-medica : Atenei Parmensis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Research Progress of DcR3 in the Diagnosis and Treatment of Sepsis.International journal of molecular sciences · 2023
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Hossein DoustkamiDepartment of Cardiology, Faculty of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran. h.doustkami@arums.ac.ir.
Leli AvestaDepartment of Cardiology, Faculty of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran. avestaleili@yahoo.com.
Behzad BabapourDepartment of Cardiology, Faculty of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran. behzadheart@yahoo.com.
Mohammad Hossein BoskabadyApplied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. boskabadymh@mums.ac.ir.
Ali NikoukhesalMedical Student, Faculty of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran.. a.nikoukhesal@gmail.com.
Mohammad Reza AslaniDepartment of Physiology, Faculty of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran.. mraslani105@yahoo.com.
Ardabil University of Medical Sciences · IRMashhad University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDecoy receptor 3 (DcR3), is a soluble receptor which is thought to have immune modulator or pro-inflammatory effects. Various risk factors have been suggested for the incidence of cardiovascular diseases (CADs) such as an increase in inflammatory factors. The purpose of the present study was to investigate the correlation of DcR3 with anthropometric, angiographic, echocardiographic, and biochemical parameters in patients with acute myocardial infarction. METHODS AND MATERIALS: A total of 90 patients who were candidates for angiography were included in the study and were divided into three groups: 30 patients with acute myocardial infarction (AMI), 30 patients with stable angina pectoris (SAP), and 30 subjects as control group with a history of chest pain but normal angiography. Anthropometric, angiographic, echocardiographic, and biochemical parameters were measured in all subjects.

resultsSerum DcR3 and interleukin (IL)-6 levels were significantly increased in patients with AMI compared with SAP and control groups (P < 0.05 to P < 0.001). In addition, there was a positive association between serum level of DcR3 and epicardial fat thickness (EFT), Gensini score, creatine kinase (CK)-MB, IL-6, and white blood cell (WBC) count in CAD patients. The results of multivariate linear regression analysis revealed that WBC count and IL-6 levels were independently associated with serum DcR3 levels.

conclusionThe current study showed an association of DcR3 and IL-6, WBC count, EFT, CK-MB, and Gensini score for the first time in male AMI patients. Increased DcR3 levels in patients with AMI may be involved in the process of atherosclerosis.

Indexed as

Coronary Artery DiseaseMyocardial InfarctionAdipose TissueBiomarkersHumansInterleukin-6Leukocyte CountMaleBiomarkersInterleukin-6

Identifiers

PMID34738600
PMCPMC8689334
OpenAlexW3209896784

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.