Evidence map›Paper›PMID 34738572›Full record

ArticleActa bio-medica : Atenei Parmensis2021

Recurrent Status Epilepticus and SARS-CoV-2 infection: the "perfect storm".

Giada Pauletto, Annacarmen Nilo, Cristian Deana, Lorenzo Verriello, Ilaria Del Negro, Christian Lettieri, Luigi Vetrugno, Mariarosaria Valente, Gian Luigi Gigli

Open access · greenAbstract readCase Reports
In one paragraph

Article in Acta bio-medica : Atenei Parmensis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. COVID-19 and Recurrent Status Epilepticus.Acta bio-medica : Atenei Parmensis · 2022
    Article
  3. Reply letter to "COVID-19 and Recurrent Status Epilepticus".Acta bio-medica : Atenei Parmensis · 2022
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Giada PaulettoNeurology Unit, Department of Neurosciences, S. Maria della Misericordia University Hospital, Udine, Italy. GIADA.PAULETTO@ASUFC.SANITA.FVG.IT.
Annacarmen NiloClinical Neurology Unit, Department of Neurosciences, S. Maria della Misericordia University Hospital, Udine, Italy. ANNACARMEN.NILO@ASUFC.SANITA.FVG.IT.
Cristian DeanaAnesthesia and Intensive Care Unit 1, Department of Anesthesia and Intensive Care, Azienda Sanitaria Universitaria Friuli Centrale, Udine, Italy.. deana.cristian@gmail.com.
Lorenzo VerrielloNeurology Unit, Department of Neurosciences, S. Maria della Misericordia University Hospital, Udine, Italy. LORENZO.VERRIELLO@ASUFC.SANITA.FVG.IT.
Ilaria Del NegroClinical Neurology Unit, Department of Neurosciences, S. Maria della Misericordia University Hospital, Udine, Italy. ILARIA.DELNEGRO@SPES.UNIUD.IT.
Christian LettieriNeurology Unit, Department of Neurosciences, S. Maria della Misericordia University Hospital, Udine, Italy. CHRISTIAN.LETTIERI@ASUFC.SANITA.FVG.IT.
Luigi VetrugnoClinical Anesthesia and Intensive Care, Department of Medicine (DAME), University of Udine Medical School, Udine, Italy. LUIGI.VETRUGNO@UNIUD.IT.
Mariarosaria ValenteClinical Neurology Unit, Department of Neurosciences, S. Maria della Misericordia University Hospital, Udine, Italy. MARIAROSARIA.VALENTE@ASUFC.SANITA.FVG.IT.
Gian Luigi GigliClinical Neurology Unit, Department of Neurosciences, S. Maria della Misericordia University Hospital, Udine, Italy. GIANLUIGI.GIGLI@UNIUD.IT.
Ospedale Santa Maria della Misericordia di Udine · ITUniversity of Udine · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Respiratory involvement is the most common clinical manifestation of COVID-19, but neurological symptoms and complications are increasingly being recognized. Seizures and status epilepticus (SE) have been described as possible consequences of hypoxia and metabolic derangements during SARS-CoV-2 infection, direct viral invasion of the central nervous system, or as para or post-infectious complications. Single episodes of SE have been described, occurring during the acute phase of COVID-19 or once the patients have been recovered. Herein, we present the case of a patient with a positive serology test for SARS-CoV-2 (IgG+, IgM-) and recurrent SE occurring within 36 days. Diagnostic work-up ruled out other known causes of SE. A post-COVID-19 infectious inflammatory/immune response is hypothesized as the possible trigger of SE.

Indexed as

COVID-19Status EpilepticusCOVID-19 TestingHumansSARS-CoV-2Serologic Tests

Identifiers

PMID34738572
PMCPMC8689343
OpenAlexW3209525952

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.