Evidence map›Paper›PMID 34738467›Full record

ArticleJournal of the American Chemical Society2021

Site-Selective α-C-H Functionalization of Trialkylamines via Reversible Hydrogen Atom Transfer Catalysis.

Yangyang Shen, Ignacio Funez-Ardoiz, Franziska Schoenebeck, Tomislav Rovis

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. B(COrganic letters · 2026
    Article
  3. Article
  4. Article
  5. Chemical Tagging ofJournal of the American Chemical Society · 2025
    Article
  6. Review
  7. Review
  8. SelectiveThe Journal of organic chemistry · 2025
    Article
  9. Article
  10. Regiodivergent α- and β-Functionalization of SaturatedJournal of the American Chemical Society · 2025
    Article
  11. Ir/Ni Metallaphotoredox Catalysis for the C(spChemistry (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Site-selective α-C(spNature communications · 2024
    Article
  17. Organophotocatalytic α-deuteration of unprotected primary aminesChemical communications (Cambridge, England) · 2024
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yangyang ShenDepartment of Chemistry, Columbia University, New York, New York 10027, United States.ORCID 0000-0003-4607-9722
Ignacio Funez-ArdoizInstitute of Organic Chemistry, RWTH Aachen University, 52047 Aachen, Germany.
Franziska SchoenebeckInstitute of Organic Chemistry, RWTH Aachen University, 52047 Aachen, Germany.
Tomislav RovisDepartment of Chemistry, Columbia University, New York, New York 10027, United States.ORCID 0000-0001-6287-8669

Funding

Selective Functionalization of Aliphatic Amines - Supplement to Support Mariah RamosR01GM125206 · NIGMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI ROVIS, TOMISLAV · 2017 to 2024
$2.6M
NIGMS NIH HHS R01 GM125206
6 · The paper itself

Abstract

Trialkylamines are widely found in naturally occurring alkaloids, synthetic agrochemicals, biological probes, and especially pharmaceuticals agents and preclinical candidates. Despite the recent breakthrough of catalytic alkylation of dialkylamines, the selective α-C(sp

Indexed as

AlkylationAminesCatalysisCoordination ComplexesFree RadicalsHydrogenIridiumModels, ChemicalSilanesSulfhydryl CompoundsAminesCoordination ComplexesFree RadicalsHydrogenIridiumSilanesSulfhydryl Compounds

Identifiers

PMID34738467
PMCPMC8855485

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.