Evidence map›Paper›PMID 34738156›Full record

ArticleCell and tissue research2022

Vangl2 participates in the primary ciliary assembly under low fluid shear stress in hUVECs.

Xin Sheng, Shuanglin Gao, Yan Sheng, Xiadan Xie, Junhua Wang, Yan He

Abstract read
PubMed Publisher
In one paragraph

Article in Cell and tissue research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Xin Sheng *Department of Biochemistry, Zunyi Medical University, Zunyi, 563000, People's Republic of China. xshengbio@163.com.ORCID http://orcid.org/0000-0002-7700-5606
Shuanglin Gao *Department of Biochemistry, Zunyi Medical University, Zunyi, 563000, People's Republic of China.
Yan ShengLaboratory of Basic Medical Morphology, Zunyi Medical University, Zunyi, 563000, People's Republic of China.
Xiadan XieDepartment of Biochemistry, Zunyi Medical University, Zunyi, 563000, People's Republic of China.
Junhua WangDepartment of Biochemistry, Zunyi Medical University, Zunyi, 563000, People's Republic of China.
Yan HeDepartment of Biochemistry, Zunyi Medical University, Zunyi, 563000, People's Republic of China.
Zunyi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pattern of blood fluid shear stress (FSS) is considered the main factor that affects ciliogenesis in human umbilical vein endothelial cells (hUVECs), the underlying mechanism is unclear. Microfluidic chamber experiments were carried out to load hUVECs with low fluid shear stress (LSS, 0.1 dynes/cm

Indexed as

CiliaHumansHuman Umbilical Vein Endothelial CellsIntracellular Signaling Peptides and ProteinsMembrane ProteinsShear StrengthTranscription FactorsIntracellular Signaling Peptides and ProteinsMembrane ProteinsTranscription FactorsVANGL2 protein, humanBasal bodyCiliogenesisFluid shear stressPrimary ciliaVangl2

Identifiers

PMID34738156
OpenAlexW3208022669

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.