Evidence map›Paper›PMID 34738062›Full record

ArticleEuropean heart journal. Case reports2021

A case report of ventricular septal defect complicating transcatheter aortic valve implant for aortic regurgitation: novel complication and technical considerations.

Jack Hartnett, Lisa Brandon, Deirdre Waterhouse, Ross T Murphy, Kevin P Walsh, Mark S Spence, Andrew O Maree

Open access · goldAbstract readCase Reports
In one paragraph

Article in European heart journal. Case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 79% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Jack HartnettDepartment of Cardiology, St James's Hospital, James's Street, Dublin 8 D08 W9RT, Ireland.ORCID https://orcid.org/0000-0001-8066-1914
Lisa BrandonDepartment of Cardiology, St James's Hospital, James's Street, Dublin 8 D08 W9RT, Ireland.ORCID https://orcid.org/0000-0001-5833-1986
Deirdre WaterhouseDepartment of Cardiology, Blackrock Clinic, Rock Road, Blackrock, Co Dublin A94 E4X7, Ireland.
Ross T MurphyDepartment of Cardiology, St James's Hospital, James's Street, Dublin 8 D08 W9RT, Ireland.
Kevin P WalshDepartment of Cardiology, Our Lady's Children's Hospital Crumlin, Dublin 12 D12 N512, Ireland.
Mark S SpenceDepartment of Cardiology, Royal Victoria Hospital, Belfast Trust, 274 Grosvenor Road, Belfast BT12 6BA, UK.
Andrew O MareeDepartment of Cardiology, St James's Hospital, James's Street, Dublin 8 D08 W9RT, Ireland.ORCID https://orcid.org/0000-0002-0002-5828
St. James's Hospital · IEChildren's Health Ireland at Crumlin · IEUniversity of Ulster · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTranscatheter aortic valve implantation (TAVI) has proven efficacy in the treatment of aortic stenosis (AS). Understandably, there is increasing enthusiasm for its use to treat aortic regurgitation (AR). However, there are significant anatomical differences between AS and AR which make TAVI for AR more complex. CASE SUMMARY: We present the case of technically challenging TAVI for severe AR, which was complicated by a traumatic ventricular septal defect (VSD) that required percutaneous closure. To our knowledge, this is the first published case of VSD post-TAVI for AR. DISCUSSION: This unanticipated complication highlights anatomical differences between TAVI use in AS and AR. Lack of aortic valve calcification and excessive annular compliance made stable deployment of a self-expanding valve extremely challenging. Despite device oversizing, repeated embolization of the prosthesis into the left ventricular outflow tract traumatized the interventricular septum.

Indexed as

Aortic regurgitationCase reportTranscatheter aortic valve implantationVentricular septal defect

Identifiers

PMID34738062
PMCPMC8564692
OpenAlexW3203412933

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.