Evidence map›Paper›PMID 34738048›Full record

ArticleJCO precision oncology2021

Clinical Utility of Functional Precision Medicine in the Management of Recurrent/Relapsed Childhood Rhabdomyosarcoma.

Arlet M Acanda De La Rocha, Maggie Fader, Ebony R Coats, Paula S Espinal, Vanessa Berrios, Cima Saghira, Ileana Sotto, Rojesh Shakya, Michelin Janvier, Ziad Khatib and 7 more

Registry-linked trialAbstract readCase Reports
In one paragraph

Article in JCO precision oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03860376 (Personalized Ex Vivo Drug Screening and Genomics Profiling to Guide Individualized Treatments for Children With Relapsed or Refractory Solid Tumors and Leukemias), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03860376 completednot on this map

Personalized Ex Vivo Drug Screening and Genomics Profiling to Guide Individualized Treatments for Children With Relapsed or Refractory Solid Tumors and Leukemias

TypeobservationalSponsorFlorida International UniversityRan2019 to 2022Enrolled25ConditionsRecurrent Childhood Acute Myeloid Leukemia, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Large Cell Lymphoma, Refractory Childhood Acute Lymphoblastic Leukemia
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Case Report: Application ofFrontiers in oncology · 2025
    Article
  3. Article
  4. Observational
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Arlet M Acanda De La RochaDepartment of Environmental Health Sciences, Robert Stempel College of Public Health & Social Work, Florida International University, Miami, FL.ORCID 0000-0002-0426-632X
Maggie FaderPersonalized Medicine Initiative, Nicklaus Children's Hospital, Miami, FL.ORCID 0000-0002-2544-4703
Ebony R CoatsDepartment of Environmental Health Sciences, Robert Stempel College of Public Health & Social Work, Florida International University, Miami, FL.ORCID 0000-0001-9424-4468
Paula S EspinalPersonalized Medicine Initiative, Nicklaus Children's Hospital, Miami, FL.
Vanessa BerriosDepartment of Environmental Health Sciences, Robert Stempel College of Public Health & Social Work, Florida International University, Miami, FL.
Cima SaghiraMiller School of Medicine, University of Miami, Miami, FL.
Ileana SottoPersonalized Medicine Initiative, Nicklaus Children's Hospital, Miami, FL.
Rojesh ShakyaDepartment of Environmental Health Sciences, Robert Stempel College of Public Health & Social Work, Florida International University, Miami, FL.
Michelin JanvierPersonalized Medicine Initiative, Nicklaus Children's Hospital, Miami, FL.
Ziad KhatibPersonalized Medicine Initiative, Nicklaus Children's Hospital, Miami, FL.
Haneen AbdellaPersonalized Medicine Initiative, Nicklaus Children's Hospital, Miami, FL.
Mathew BittlePersonalized Medicine Initiative, Nicklaus Children's Hospital, Miami, FL.
Cristina M Andrade-FeraudDepartment of Environmental Health Sciences, Robert Stempel College of Public Health & Social Work, Florida International University, Miami, FL.
Tomás R GuilarteDepartment of Environmental Health Sciences, Robert Stempel College of Public Health & Social Work, Florida International University, Miami, FL.ORCID 0000-0002-5376-6347
Jennifer McCafferty-FernandezPersonalized Medicine Initiative, Nicklaus Children's Hospital, Miami, FL.
Daria SalyakinaPersonalized Medicine Initiative, Nicklaus Children's Hospital, Miami, FL.ORCID 0000-0003-3283-3691
Diana J AzzamDepartment of Environmental Health Sciences, Robert Stempel College of Public Health & Social Work, Florida International University, Miami, FL.ORCID 0000-0002-2605-8855

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antineoplastic Combined Chemotherapy ProtocolsChildDrug Screening Assays, AntitumorFemaleHumansNeoplasm Recurrence, LocalPositron-Emission TomographyPrecision MedicineRhabdomyosarcoma

Identifiers

PMID34738048
PMCPMC8563073

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.