Evidence map›Paper›PMID 34737985›Full record

ReviewPreventive nutrition and food science2021

Carotenoids: Therapeutic Strategy in the Battle against Viral Emerging Diseases, COVID-19: An Overview.

Ayman Khalil, Diana Tazeddinova, Khaled Aljoumaa, Zhumayeva Araigul Kazhmukhanbetkyzy, Ayan Orazov, Abduvali Djabarovich Toshev

Open access · bronzeAbstract readReview
In one paragraph

Review in Preventive nutrition and food science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 50 citations in OpenAlex.

  1. Bioactive potential of biomass and lipids of halophilic cyanobacterium and microalgae.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Antiviral Activity ofPathogens (Basel, Switzerland) · 2025
    Article
  6. Therapeutic Use ofAnimals : an open access journal from MDPI · 2025
    Article
  7. Review
  8. Review
  9. Article
  10. Frontiers in microbiology · 2024
    Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Review
  18. F1000Research · 2023
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ayman KhalilDepartment of Food technology, South Ural State University, Chelyabinsk 454080, Russian Federation.ORCID https://orcid.org/0000-0001-5054-7408
Diana TazeddinovaDepartment of Food technology, South Ural State University, Chelyabinsk 454080, Russian Federation.ORCID https://orcid.org/0000-0002-8052-0692
Khaled AljoumaaDepartment of Food technology, South Ural State University, Chelyabinsk 454080, Russian Federation.ORCID https://orcid.org/0000-0001-6850-4131
Zhumayeva Araigul KazhmukhanbetkyzyHigher School of Technologies of Food and Processing Productions, Zhangir Khan University, Uralsk 090009, The Republic of Kazakhstan.ORCID https://orcid.org/0000-0001-7637-8155
Ayan OrazovHigher School of Technologies of Food and Processing Productions, Zhangir Khan University, Uralsk 090009, The Republic of Kazakhstan.ORCID https://orcid.org/0000-0003-2191-1295
Abduvali Djabarovich ToshevDepartment of Food technology, South Ural State University, Chelyabinsk 454080, Russian Federation.ORCID https://orcid.org/0000-0001-8620-2065
South Ural State University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carotenoids, a group of phytochemicals, are naturally found in the Plant kingdom, particularly in fruits, vegetables, and algae. There are more than 600 types of carotenoids, some of which are thought to prevent disease, mainly through their antioxidant properties. Carotenoids exhibit several biological and pharmaceutical benefits, such as anti-inflammatory, anti-cancer, and immunity booster properties, particularly as some carotenoids can be converted into vitamin A in the body. However, humans cannot synthesize carotenoids and need to obtain them from their diets or via supplementation. The emerging zoonotic virus severe acute respiratory syndrome coronavirus 2, which causes coronavirus disease 2019 (COVID-19), originated in bats, and was transmitted to humans. COVID-19 continues to cause devastating international health problems worldwide. Therefore, natural preventive therapeutic strategies from bioactive compounds, such as carotenoids, should be appraised for strengthening physiological functions against emerging viruses. This review summarizes the most important carotenoids for human health and enhancing immunity, and their potential role in COVID-19 and its related symptoms. In conclusion, promising roles of carotenoids as treatments against emerging disease and related symptoms are highlighted, most of which have been heavily premeditated in studies conducted on several viral infections, including COVID-19. Further

Indexed as

anti-inflammatoryantioxidantsantiviral agentscarotenoidsCOVID-19

Identifiers

PMID34737985
PMCPMC8531419
OpenAlexW3203435481

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.