Evidence map›Paper›PMID 34737914›Full record

ReviewCureus2021

A Substantive Narrative Review on the Usage of Lidocaine in Cataract Surgery.

Akshay J Reddy, Allen Dang, Amy A Dao, Gordon Arakji, Joshua Cherian, Hetal Brahmbhatt

2 registry-linked trialsAbstract readReview
In one paragraph

Review in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06325397 completednot on this mapstarted 2024, after this paper: background citation

Less Discomfort and Less Pharmacology. Cataract Surgery at Physiologic Intraocular Pressure (IOP)

TypeobservationalSponsorMatthew RauenRan2024 to 2025Enrolled65ConditionsNuclear CataractArmsHigh Intraocular Pressure (IOP), Low Intraocular Pressure (IOP)
NCT07223866 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

The Impact of Physiologic Cataract Surgery on Patient Comfort and Medication Usage

TypeinterventionalSponsorMatthew RauenRan2025 to 2027Enrolled85ConditionsCataract and IOL Surgery, Cataract Surgery Anesthesia, Cataract Surgery Experience, Nuclear CataractArmsHigh IOP Setting, Low IOP Setting
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Akshay J ReddyOpthalmology, California Northstate University College of Medicine, Elk Grove, USA.
Allen DangAnaesthesia, California Northstate University College of Medicine, Elk Grove, USA.
Amy A DaoOpthalmology, California Northstate University College of Medicine, Elk Grove, USA.
Gordon ArakjiHealth Sciences, California Northstate University College of Health Sciences, Rancho Cordova, USA.
Joshua CherianHealth Sciences, California Northstate University College of Health Sciences, Rancho Cordova, USA.
Hetal BrahmbhattPsychiatry, Mercy General Hospital, Sacramento, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cataracts are a disease that causes a gradual decrease in visual prowess and requires surgery when the symptoms progress to an abhorrent state. This disease can be treated through surgical procedures that use anesthetics, such as lidocaine. Through inhibiting sensory nerve propagation to the brain, lidocaine plays an invaluable part in reducing pain for patients that undergo cataract surgery. Current clinical practice commonly utilizes 2% lidocaine with fentanyl as a combination agent. However, recent studies have reported that concentrations higher than 1% can cause substantial alteration to corneal epithelium cells. Additionally, fentanyl is cited as an extremely addictive opioid inappropriate for continual use in cataract surgeries. In this review, the authors examine the application and concentration of lidocaine, along with the various combination agents that were reported in several studies that describe the usage of the anesthetic during cataract surgery. Within the review, it was found that most surgeons generally only use lidocaine gel on the corneal epithelium tissue of patients during cataract surgery. Perhaps this standard could change over time as it is generally known that using intracameral injections in conjunction with topical anesthesia produces better patient outcomes. The authors find that although anesthetics and surgical treatment for cataracts are generally beneficial for patients, there are still many adjustments that could be implemented to enhance patient outcomes.

Indexed as

cataractcorneal epitheliumfentanyllidocainephenylephrine

Identifiers

PMID34737914
PMCPMC8559888

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.