Evidence map›Paper›PMID 34737889›Full record

ArticleFuture science OA2021

Coexpression network analysis identified lncRNAs-mRNAs with potential relevance in African ancestry prostate cancer.

Rafael Parra-Medina, Liliana López-Kleine, Sandra Ramírez-Clavijo, César Payán-Gómez

Abstract read
In one paragraph

Article in Future science OA, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rafael Parra-MedinaFaculty of Natural Sciences, Universidad del Rosario, Bogotá, Colombia.ORCID https://orcid.org/0000-0002-8428-5837
Liliana López-KleineDepartment of Statistics, Faculty of Science, Universidad Nacional de Colombia, Bogotá, Colombia.ORCID https://orcid.org/0000-0001-9325-9529
Sandra Ramírez-ClavijoFaculty of Natural Sciences, Universidad del Rosario, Bogotá, Colombia.ORCID https://orcid.org/0000-0003-0336-5614
César Payán-GómezFaculty of Natural Sciences, Universidad del Rosario, Bogotá, Colombia.ORCID https://orcid.org/0000-0002-0633-1332

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThis study aims to investigate similarities and differences using lncRNA and mRNA coexpression network analysis in African ancestry (AA) and European ancestry (EA) among prostate cancer (PCa) patients.

methodsWe performed weighted gene coexpression network analysis of the expression from 49 of AA and 49 of EA to identify lncRNAs-mRNAs.

results27 lncRNAs and 36 mRNAs were highly expressed in patients of AA. Two mRNAs and their antisense lncRNAs were expressed. Additionally, seven mRNAs were DE or coexpressed and had an impact on survival.

conclusionWe present a list of lncRNAs and mRNAs that were DE and coexpressed when comparing patients of AA and EA, and these data are a resource for future studies to understand the role of lncRNAs.

Indexed as

AfricanancestrycoexpressionlncRNAmRNAprostate cancer

Identifiers

PMID34737889
PMCPMC8558852

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