Evidence map›Paper›PMID 34737884›Full record

ArticleFuture science OA2021

Advanced dermatofibrosarcoma protuberans: an updated analysis of cases from an Indian sarcoma clinic.

Azgar A Rasheed, Adarsh Barwad, Ekta Dhamija, Rakesh Garg, Rambha Pandey, Shamim A Shamim, Sreedharan T Arun Raj, Sameer Rastogi

Abstract read
In one paragraph

Article in Future science OA, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Azgar A RasheedDepartment of Medical Oncology, BRA-IRCH, All India Institute of Medical Sciences, New Delhi, 110029, India.ORCID https://orcid.org/0000-0003-2217-5699
Adarsh BarwadDepartment of Pathology, All India Institute of Medical Sciences, New Delhi, 110029, India.
Ekta DhamijaDepartment of Radiodiagnosis, BRA-IRCH, All India Institute of Medical Sciences, New Delhi, 110029, India.
Rakesh GargDepartment of Onco-Anaesthesia & Palliative Medicine, BRA-IRCH, All India Institute of Medical Sciences, New Delhi, 110029, India.ORCID https://orcid.org/0000-0001-5842-8024
Rambha PandeyDepartment of Radiation Oncology, BRA-IRCH, All India Institute of Medical Sciences, New Delhi, 110029, India.
Shamim A ShamimDepartment of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, 110029, India.ORCID https://orcid.org/0000-0001-8787-4285
Sreedharan T Arun RajDepartment of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, 110029, India.
Sameer RastogiDepartment of Medical Oncology, BRA-IRCH, All India Institute of Medical Sciences, New Delhi, 110029, India.ORCID https://orcid.org/0000-0003-4792-3083

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimDermatofibrosarcoma protuberans (DFSP) accounts for less than 2% of all soft-tissue sarcomas. PATIENTS &

methodsWe retrospectively reviewed our database for patients with locally advanced or metastatic DFSP who had presented to our clinic between January 2016 and January 2020.

resultsWe identified a total of 14 patients, of whom ten had sarcomatous transformation. Eleven cases had metastatic disease and three were locally advanced. The initial partial response rate to first-line imatinib was 76.9% and the overall median progression-free survival on imatinib was 15 months.

conclusionWe had a high proportion of patients with sarcomatous transformation, in contrast to their relative rarity in the West. While most patients had initial good responses to imatinib, second-line therapies were not as effective.

Indexed as

advanced DFSPdermatofibrosarcoma protuberansfibrosarcomatous DFSPimatinibmetastatic DFSP

Identifiers

PMID34737884
PMCPMC8558865

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.