Evidence map›Paper›PMID 34737877›Full record

ArticleRoyal Society open science2021

Detection and genetic characterization of the novel torque teno virus group 6 in Taiwanese general population.

Kuang-Liang Hsiao, Li-Yu Wang, Ju-Chien Cheng, Yu-Jung Cheng, Chiung-Ling Lin, Hsin-Fu Liu

Open access · goldAbstract read
In one paragraph

Article in Royal Society open science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Torque Teno Virus: A Promising Biomarker in Kidney Transplant Recipients.International journal of molecular sciences · 2024
    Article
  6. Comparison ofFrontiers in microbiology · 2023
    Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Kuang-Liang HsiaoDepartment of Medical Research, MacKay Memorial Hospital, Taipei, Taiwan.ORCID 0000-0003-4397-7762
Li-Yu WangDepartment of Medicine, MacKay Medical College, New Taipei City, Taiwan.
Ju-Chien ChengDepartment of Medical Laboratory Science and Biotechnology, China Medical University, Taichung, Taiwan.
Yu-Jung ChengDepartment of Bioscience and Biotechnology, National Taiwan Ocean University, Keelung, Taiwan.
Chiung-Ling LinDepartment of Medical Research, MacKay Memorial Hospital, Taipei, Taiwan.
Hsin-Fu LiuDepartment of Medical Research, MacKay Memorial Hospital, Taipei, Taiwan.ORCID 0000-0003-0082-2269
National Taiwan Ocean University · TWChina Medical University · TWMackay Medical University · TWMackay Memorial Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Torque teno virus (TTV) is one of the most common human viruses and can infect an individual with multiple genotypes chronically and persistently. TTV group 6 is a recently discovered phylogenetic group first isolated from eastern Taiwan indigenes, but whether the TTV group 6 was also prevalent in the general population still unknown. One hundred and three randomly collected blood samples from general population and 66 TTV positive DNA samples extracted from Taiwan indigenes were included. A group-6-specific PCR was developed for re-screen over TTV positive samples. Two TTV group 6 positive samples from general population were cloned and sequenced for identifying mix-infected TTVs and confirming their classification by maximum-likelihood and Bayesian inference phylogeny. TTV group 6 can be detected in 4.5% (4/89) and 7.6% (5/66) of TTV positive samples from Taiwanese general population and eastern Taiwan indigenes, respectively. Sample VC09 was mix-infected with TTV groups 3 and 6. Sample VC99 was mix-infected with TTV groups 3, 4 and 6. A highly diverse triple overlapping region was observed, which may represent a unique phenomenon of TTV. The group-6-specific PCR can successfully detect TTV group 6. TTV group 6 may be prevalent worldwide regardless of the geographic region and/or ethnic groups.

Indexed as

anellovirusgroup 6phylogenetic analysisTaiwanTTV

Identifiers

PMID34737877
PMCPMC8564604
OpenAlexW3209741087

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.