Evidence map›Paper›PMID 34737811›Full record

ReviewExperimental and therapeutic medicine2021

New perspectives on the roles of circular RNAs in osteoarthritis development and progression (Review).

Guoding Cao, Yuqi Pei, Peng Li, Peng Liu, Yapeng Deng, Yu Gao, Jun Liu, Xusheng Li

Open access · diamondAbstract readReview
In one paragraph

Review in Experimental and therapeutic medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Guoding CaoDepartment of Orthopedics, Affiliated Hospital of Gansu Medical College, Pingliang, Gansu 744000, P.R. China.
Yuqi PeiGansu University of Traditional Chinese Medicine, Lanzhou, Gansu 730000, P.R. China.
Peng LiDepartment of Orthopedics, The 940th Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army, Lanzhou, Gansu 730050, P.R. China.
Peng LiuDepartment of Orthopedics, The 940th Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army, Lanzhou, Gansu 730050, P.R. China.
Yapeng DengDepartment of Orthopedics, The 940th Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army, Lanzhou, Gansu 730050, P.R. China.
Yu GaoDepartment of Orthopedics, The 940th Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army, Lanzhou, Gansu 730050, P.R. China.
Jun LiuDepartment of Orthopedics, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shanxi 710061, P.R. China.
Xusheng LiDepartment of Orthopedics, The 940th Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army, Lanzhou, Gansu 730050, P.R. China.
Chinese People's Liberation Army · CNGansu University of Traditional Chinese Medicine · CNPingliang People's Hospital · CNSecond Affiliated Hospital of Xi'an Jiaotong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoarthritis (OA) is a common disease of the elderly, posing a major personal and socioeconomic burden. OA is characterized by painful degeneration of articular cartilage, and its prevention, diagnosis and treatment remain problematic. Circular RNAs (circRNAs) constitute a large family of non-coding RNAs that are widely distributed, stable, conserved and tissue-specific. circRNAs have been found to be closely associated with OA development and progression, and they may serve as targets for disease prevention and treatment. The aim of the present article was to review the roles of circRNAs in OA and discuss possible treatment strategies.

Indexed as

chondrocytecircular RNAextracellular matrixosteoarthritis

Identifiers

PMID34737811
PMCPMC8561767
OpenAlexW3205745558

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.