Evidence map›Paper›PMID 34737739›Full record

ReviewFrontiers in immunology2021

The Genomic Organization of the

Lisanne Storm, Jesse Bruijnesteijn, Natasja G de Groot, Ronald E Bontrop

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Immune checkpoint for pregnancy.Seminars in immunopathology · 2025
    Review
  3. Natural killer cells in multiple sclerosis: foe or friends?Frontiers in cellular neuroscience · 2025
    Review
  4. Frontiers in immunology · 2025
    Article
  5. Review
  6. Article
  7. Review
  8. Identification of the hybrid geneFrontiers in immunology · 2024
    Article
  9. Activation of immune signals during organ transplantation.Signal transduction and targeted therapy · 2023
    Review
  10. Article
  11. Review
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Lisanne StormComparative Genetics and Refinement, Biomedical Primate Research Centre, Rijswijk, Netherlands.
Jesse BruijnesteijnComparative Genetics and Refinement, Biomedical Primate Research Centre, Rijswijk, Netherlands.
Natasja G de GrootComparative Genetics and Refinement, Biomedical Primate Research Centre, Rijswijk, Netherlands.
Ronald E BontropComparative Genetics and Refinement, Biomedical Primate Research Centre, Rijswijk, Netherlands.
Biomedical Primate Research Centre · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The genes of the leukocyte immunoglobulin-like receptor (LILR) family map to the leukocyte receptor complex (LRC) on chromosome 19, and consist of both activating and inhibiting entities. These receptors are often involved in regulating immune responses, and are considered to play a role in health and disease. The human

Indexed as

Conserved SequenceEvolution, MolecularGenomicsMultigene FamilyAnimalsDisease SusceptibilityGene Expression RegulationGenetic LociGenetic MarkersHomeostasisHominidaeHumansPhylogenyPrimatesReceptors, KIRTandem Repeat SequencesGenetic MarkersKIR3DX1 protein, humanReceptors, KIRhumanimmunoglobulin Ig-like superfamily (IgSF)killer immunoglobulin-like receptor (KIR)leukocyte immunoglobulin-like receptor (LILR)leukocyte receptor complex (LRC)non-human primates (NHP)

Identifiers

PMID34737739
PMCPMC8562567
OpenAlexW3205933316

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.