Evidence map›Paper›PMID 34737737›Full record

ReviewFrontiers in immunology2021

To bnAb or Not to bnAb: Defining Broadly Neutralising Antibodies Against HIV-1.

Sarah A Griffith, Laura E McCoy

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. In vivo evolution of env in SHIV-AD8Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sarah A GriffithDivision of Infection and Immunity, Institute of Immunity and Transplantation, University College London, London, United Kingdom.
Laura E McCoyDivision of Infection and Immunity, Institute of Immunity and Transplantation, University College London, London, United Kingdom.
University College London · GB

Funding

Medical Research Council MR/R008698/1
6 · The paper itself

Abstract

Since their discovery, antibodies capable of broad neutralisation have been at the forefront of HIV-1 research and are of particular interest due to

Indexed as

Broadly Neutralizing AntibodiesHIV-1HIV AntibodiesHIV InfectionsHumansBroadly Neutralizing AntibodiesHIV Antibodiesbroadly neutralising antibodycomplementary determining regionepitopeHIV-1somatic hypermutation

Identifiers

PMID34737737
PMCPMC8560739
OpenAlexW3205173377

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.