Evidence map›Paper›PMID 34737724›Full record

ReviewFrontiers in endocrinology2021

New Regions With Molecular Alterations in a Rare Case of Insulinomatosis: Case Report With Literature Review.

Kirill Anoshkin, Ivan Vasilyev, Kristina Karandasheva, Mikhail Shugay, Valeriya Kudryavtseva, Alexey Egorov, Larisa Gurevich, Anna Mironova, Alexey Serikov, Sergei Kutsev and 1 more

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Kirill AnoshkinLaboratory of Epigenetics, Research Centre for Medical Genetics, Moscow, Russia.
Ivan VasilyevI.M. Sechenov First Moscow State Medical University, Moscow, Russia.
Kristina KarandashevaLaboratory of Epigenetics, Research Centre for Medical Genetics, Moscow, Russia.
Mikhail ShugayPirogov Russian National Research Medical University, Moscow, Russia.
Valeriya KudryavtsevaLaboratory of Epigenetics, Research Centre for Medical Genetics, Moscow, Russia.
Alexey EgorovI.M. Sechenov First Moscow State Medical University, Moscow, Russia.
Larisa GurevichMorphological Department of Oncology, M.F. Vladimirsky Moscow Regional Research and Clinical Institute, Moscow, Russia.
Anna MironovaI.M. Sechenov First Moscow State Medical University, Moscow, Russia.
Alexey SerikovI.M. Sechenov First Moscow State Medical University, Moscow, Russia.
Sergei KutsevLaboratory of Epigenetics, Research Centre for Medical Genetics, Moscow, Russia.
Vladimir StrelnikovLaboratory of Epigenetics, Research Centre for Medical Genetics, Moscow, Russia.
Research Centre for Medical Genetics · RUSechenov University · RUMoscow Regional Research Institute of Obstetrics and Gynecology · RUPrivolzhsky Research Medical University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Insulinomatosis is characterized by monohormonality of multiple macro-tumors and micro-tumors that arise synchronously and metachronously in all regions of the pancreas, and often recurring hypoglycemia. One of the main characteristics of insulinomatosis is the presence of insulin-expressing monohormonal endocrine cell clusters that are exclusively composed of proliferating insulin-positive cells, are less than 1 mm in size, and show solid islet-like structure. It is presumed that insulinomatosis affects the entire population of β-cells. With regards to molecular genetics, this phenomenon is not related to mutation in

Indexed as

DNA Copy Number VariationsAgedHumansInsulinomaMaleMiddle AgedPancreasPancreatic NeoplasmsCEBPAcopy number variationFOXL2insulinomatosisIRS2neuroendocrine tumors

Identifiers

PMID34737724
PMCPMC8563021
OpenAlexW3205175856

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.