Evidence map›Paper›PMID 34737597›Full record

ArticleClinical, cosmetic and investigational dermatology2021

Dietary Habits in Japanese Patients with Alopecia Areata.

Teppei Hagino, Shizuka Okazaki, Naotaka Serizawa, Kaori Suzuki, Mio Kaga, Yohei Otsuka, Erina Mikami, Toshihiko Hoashi, Hidehisa Saeki, Hiroki Matsuda and 2 more

Open access · goldAbstract read
In one paragraph

Article in Clinical, cosmetic and investigational dermatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Deciphering the Complex Immunopathogenesis of Alopecia Areata.International journal of molecular sciences · 2024
    Review
  4. Review
  5. Article
  6. Review
  7. Lifestyle Factors Involved in the Pathogenesis of Alopecia Areata.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Teppei HaginoDepartment of Dermatology, Nippon Medical School Chiba Hokusoh Hospital, Inzai, Chiba, Japan.
Shizuka OkazakiDepartment of Dermatology, Nippon Medical School Chiba Hokusoh Hospital, Inzai, Chiba, Japan.
Naotaka SerizawaDepartment of Dermatology, Nippon Medical School Chiba Hokusoh Hospital, Inzai, Chiba, Japan.
Kaori SuzukiDepartment of Dermatology, Nippon Medical School Chiba Hokusoh Hospital, Inzai, Chiba, Japan.
Mio KagaDepartment of Dermatology, Nippon Medical School, Tokyo, Japan.
Yohei OtsukaDepartment of Dermatology, Nippon Medical School, Tokyo, Japan.
Erina MikamiDepartment of Dermatology, Nippon Medical School, Tokyo, Japan.
Toshihiko HoashiDepartment of Dermatology, Nippon Medical School, Tokyo, Japan.
Hidehisa SaekiDepartment of Dermatology, Nippon Medical School, Tokyo, Japan.ORCID 0000-0002-1095-0355
Hiroki MatsudaDepartment of Dermatology, Tokyo Teishin Hospital, Tokyo, Japan.
Hiroshi MitsuiDepartment of Dermatology, Tokyo Teishin Hospital, Tokyo, Japan.
Naoko KandaDepartment of Dermatology, Nippon Medical School Chiba Hokusoh Hospital, Inzai, Chiba, Japan.ORCID 0000-0003-4389-2312
Chiba Hokusou Hospital · JPNippon Medical School · JPTokyo Teishin Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAlopecia areata (AA) is characterized by non-scarring, patchy hair loss caused by autoimmune reactions to anagen hair follicles. The pathogenesis of AA may be affected by the diet. However, the dietary habits of patients with AA have not been precisely examined. Therefore, the aim of this study was to investigate the dietary habits of patients with AA in comparison to those of healthy controls. PATIENTS AND

methodsWe evaluated the dietary habits of 70 adult Japanese patients with AA using a brief-type self-administered diet history questionnaire and compared them to the habits of age- and sex-matched healthy controls.

resultsJapanese patients with AA had a higher body mass index (BMI) and higher intakes of vitamin C and fruit than the controls. Logistic regression analysis showed that AA was associated with BMI. Retinol intake was positively correlated with severity of alopecia tool (SALT) score, and linear regression analysis revealed that retinol intake was a predictor of SALT score. Retinol intake among patients with moderate to severe AA (ie, a SALT score >25) was higher than that in patients with mild AA (a SALT score ≤25). The mean age of AA patients with atopic dermatitis (AD) was lower than that of AA patients without AD; however, there were no differences in nutrient or food intake between these two groups. Logistic regression analysis showed that the comorbidity AD was negatively associated with age.

conclusionAA was associated with a high BMI, and high retinol intake was a predictor of SALT score. Further studies should be conducted to clarify whether dietary intervention to reduce BMI or limit retinol intake can alter the development or severity of AA.

Indexed as

atopic dermatitisbody mass indexretinolvitamin C

Identifiers

PMID34737597
PMCPMC8560057
OpenAlexW3208361211

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.