Evidence map›Paper›PMID 34737516›Full record

ArticleJournal of neurosciences in rural practice2021

Profile of Scrub Typhus Meningitis/Meningoencephalitis in Children with and without Scrub Typhus IgM Antibody in CSF.

Bijayini Behera, Amit Kumar Satapathy, Jai Ranjan, Shyam Chandrasekar, Subhakanta Patel, Baijayantimala Mishra, Samarendra Mahapatro, Rashmi Ranjan Das

Open access · goldAbstract read
In one paragraph

Article in Journal of neurosciences in rural practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Bijayini BeheraDepartment of Microbiology, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.
Amit Kumar SatapathyDepartment of Pediatrics, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.ORCID 0000-0003-1101-7847
Jai RanjanDepartment of Microbiology, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.
Shyam ChandrasekarDepartment of Pediatrics, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.
Subhakanta PatelDepartment of Pediatrics, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.
Baijayantimala MishraDepartment of Microbiology, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.
Samarendra MahapatroDepartment of Pediatrics, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.
Rashmi Ranjan DasDepartment of Pediatrics, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.
All India Institute of Medical Sciences Bhubaneswar · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this article was to study the spectrum of scrub typhus meningitis/meningoencephalitis (STM) cases in children. Children ≤14 years of age with acute undifferentiated febrile illness were included. Immunoglobulin M (IgM) enzyme-linked immunosorbent assay was done in blood and cerebrospinal fluid (CSF) of children with suspected STM. Demographic, clinical, and laboratory details were expressed as descriptive statistics. Factors associated with neurological involvement were identified on univariate analysis. A total of 76 children had ST during the study period (meningitis/meningoencephalitis = 8 [10.5%], of which 5 [62.5%] had detectable ST IgM antibodies in CSF). The included children were 4 to 12 years of age with boys > girls. Headache and vomiting were common in those with STM, whereas hyponatremia and thrombocytopenia were common in those without STM. All children with STM recovered with sequelae in one child (right lateral rectus palsy). There was no mortality. STM has an incidence of 10.5% in children with ST from Eastern India. Headache and vomiting were significant predictors of STM, whereas hyponatremia and thrombocytopenia were significant predictor of non-STM.

Indexed as

childrenmeningitismeningoencephalitisOrientia tsutsugamushiscrub typhus

Identifiers

PMID34737516
PMCPMC8559072
OpenAlexW3199375515

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.