ReviewNature reviews. Microbiology2022
Antibiotic resistance in the environment.
Review in Nature reviews. Microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07167173 (Predictive Model for Multidrug Resistance in Patients Admitted to the Emergency Department With Sepsis), which is not on this map. Cited by 1,017 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Predictive Model for Multidrug Resistance in Patients Admitted to the Emergency Department With Sepsis
Who cites it
1,017 citing papers in PubMed, 2 syntheses or guidelines pooled it, 2,613 citations in OpenAlex.
- Iran's Escherichia coli AMR Landscape (2010-2025): A One Health Systematic Review and Meta-Analysis.MicrobiologyOpen · 2026Pooled it
- Antibiotic Resistance Genes in Dust from Kindergarten Environments: A Systematic Review of Occurrence, Diversity, Determinants, and Exposure Implications.International journal of environmental research and public health · 2026Pooled it
- A network dynamical simulation model for the study of antibiotic resistance in microbial communities.Gut microbes · 2026Article
- Dietary and nutritional strategies for reducing disease risk associated with antibiotic-induced dysbiosis.Gut microbes · 2026Review
- Sewage surveillance for assessing clinical antibiotic resistance prevalence: Combining metagenomic and phenotypic data.One health (Amsterdam, Netherlands) · 2026Article
- Genotoxicity and sub-chronic oral toxicity of a blend of bacteriophage for animal feeds.Toxicology reports · 2026Article
- Biodegradation Characteristics of Piperacillin by Marine Bacillus cereus PP1 and Genome-Guided Mining of Candidate β-Lactamases.Functional & integrative genomics · 2026Article
- Antimicrobial Resistance Under a Changing Climate.Journal of the Royal Society of New Zealand · 2026Article
- Antibiotic Resistance and Biofilm-Forming Capacity of Oral Biofilm Bacteria in Patients With Periodontitis and Healthy Individuals.MicrobiologyOpen · 2026Article
- First Report of blaMicrobiologyOpen · 2026Article
- Farm-adapted multicomponent bacteriophage preparation for environmental biocontrol in commercial dairy cattle housing: A One Health approach.Veterinary world · 2026Article
- Electronic-State Programming of Ultrasmall CeOAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Biosurfactants direct the evolutionary dynamics of surface-associated microbial systems.Science advances · 2026Article
- The Spread of Antibiotic Resistance in Natural Environments.Antibiotics (Basel, Switzerland) · 2026Article
- Aquaculture Pathogens and Antimicrobial Resistance: A One Health Perspective.International journal of molecular sciences · 2026Review
- Pairwise Growth Dynamics of EnvironmentalAntibiotics (Basel, Switzerland) · 2026Article
- Article
- Soil management practices shape the abundance, diversity, and spread of antimicrobial resistance.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Soil Acidification Enriches Antibiotic Resistome.Global change biology · 2026Article
- Effects of PVA/TiOMembranes · 2026Article
957 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Antibiotic resistance is a global health challenge, involving the transfer of bacteria and genes between humans, animals and the environment. Although multiple barriers restrict the flow of both bacteria and genes, pathogens recurrently acquire new resistance factors from other species, thereby reducing our ability to prevent and treat bacterial infections. Evolutionary events that lead to the emergence of new resistance factors in pathogens are rare and challenging to predict, but may be associated with vast ramifications. Transmission events of already widespread resistant strains are, on the other hand, common, quantifiable and more predictable, but the consequences of each event are limited. Quantifying the pathways and identifying the drivers of and bottlenecks for environmental evolution and transmission of antibiotic resistance are key components to understand and manage the resistance crisis as a whole. In this Review, we present our current understanding of the roles of the environment, including antibiotic pollution, in resistance evolution, in transmission and as a mere reflection of the regional antibiotic resistance situation in the clinic. We provide a perspective on current evidence, describe risk scenarios, discuss methods for surveillance and the assessment of potential drivers, and finally identify some actions to mitigate risks.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.