Evidence map›Paper›PMID 34737359›Full record

ArticleScientific reports2021

Selenium-enriched Bacillus subtilis yb-114246 improved growth and immunity of broiler chickens through modified ileal bacterial composition.

Jiajun Yang, Jing Wang, Kehe Huang, Qingxin Liu, GuofangLiu, Xiaozhou Xu, Hao Zhang, Mengling Zhu

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Single or Combined Supplementation ofVeterinary sciences · 2025
    Article
  7. Article
  8. Animals : an open access journal from MDPI · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. A combination of selenium andFrontiers in veterinary science · 2023
    Article
  14. Article
  15. Review
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jiajun YangSchool of Animal Husbandry and Veterinary Medicine, Jiangsu Vocational College of Agriculture and Forestry, Jurong, 212400, Jiangsu, China.
Jing WangSchool of Animal Husbandry and Veterinary Medicine, Jiangsu Vocational College of Agriculture and Forestry, Jurong, 212400, Jiangsu, China.
Kehe HuangCollege of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China.
Qingxin LiuSchool of Animal Husbandry and Veterinary Medicine, Jiangsu Vocational College of Agriculture and Forestry, Jurong, 212400, Jiangsu, China.
GuofangLiuSchool of Animal Husbandry and Veterinary Medicine, Jiangsu Vocational College of Agriculture and Forestry, Jurong, 212400, Jiangsu, China.
Xiaozhou XuSchool of Animal Husbandry and Veterinary Medicine, Jiangsu Vocational College of Agriculture and Forestry, Jurong, 212400, Jiangsu, China.
Hao ZhangCollege of Animal Science and Technology, Chinese Agricultural University, Beijing, 100093, China. zhanghao827@163.com.
Mengling ZhuSchool of Animal Husbandry and Veterinary Medicine, Jiangsu Vocational College of Agriculture and Forestry, Jurong, 212400, Jiangsu, China. zhumengling@jsafc.edu.cn.
Jiangsu Agri-animal Husbandry Vocational College · CNChina Agricultural University · CNNanjing Agricultural University · CN

Funding

China Agriculture Research System of MOF and MARA (CARS-40)Innovation training program for College Students (202113103058Y)Youth support project of Jiangsu Vocational College of Agriculture and Forestry (2021kj19)
6 · The paper itself

Abstract

Here, a Selenium-enriched Bacillus subtilis (SEBS) strain was generated and supplemented to broiler chickens' diet, and the impact in ileum bacterial microbiome, immunity and body weight were assessed. In a nutshell, five hundred 1-old old chicken were randomly divided into five groups: control, inorganic Se, Bacillus subtilis (B. subtilis), SEBS, and antibiotic, and colonization with B. subtilis and SEBS in the gastrointestinal tract (GIT) were measured by fluorescence in situ hybridization (FISH) assay and quantitative real-time polymerase chain reaction (qPCR). In summary, Chicks fed SEBS or B. subtilis had higher body weight than the control chicks or those given inorganic Se. SEBS colonized in distal segments of the ileum improved bacterial diversity, reduced the endogenous pathogen burden and increased the number of Lactobacillus sp. in the ileal mucous membrane. Species of unclassified Lachnospiraceae, uncultured Anaerosporobacter, Peptococcus, Lactobacillus salivarius, and Ruminococcaceae_UCG-014, and unclassified Butyricicoccus in the ileal mucous membrane played a key role in promoting immunity. Inorganic Se supplementation also improved bacterial composition of ileal mucous membranes, but to a less extent. In conclusion, SEBS improved performance and immunity of broiler chickens through colonization and modulation of the ileal mucous membrane microbiome.

Indexed as

Animal FeedAnimal HusbandryAnimalsBacillus subtilisChickensDietDietary SupplementsGastrointestinal MicrobiomeIleumProbioticsSeleniumSelenium

Identifiers

PMID34737359
PMCPMC8568892
OpenAlexW3162405286

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.