Evidence map›Paper›PMID 34737335›Full record

ArticleScientific reports2021

Deep learning models for screening of high myopia using optical coherence tomography.

Kyung Jun Choi, Jung Eun Choi, Hyeon Cheol Roh, Jun Soo Eun, Jong Min Kim, Yong Kyun Shin, Min Chae Kang, Joon Kyo Chung, Chaeyeon Lee, Dongyoung Lee and 3 more

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Shaping the future of myopia: artificial intelligence for vitreoretinal complications of high and pathologic myopia.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Insights into artificial intelligence in myopia management: from a data perspective.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Generative adversarial network-based deep learning approach in classification of retinal conditions with optical coherence tomography images.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
    Article
  16. Article
  17. Artificial intelligence technology for myopia challenges: A review.Frontiers in cell and developmental biology · 2023
    Review
  18. Advances in OCT Imaging in Myopia and Pathologic Myopia.Diagnostics (Basel, Switzerland) · 2022
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Kyung Jun ChoiDepartment of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, #81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea.
Jung Eun ChoiMedical AI Research Center, Samsung Medical Center, #81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea.
Hyeon Cheol RohDepartment of Ophthalmology, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Republic of Korea.
Jun Soo EunDepartment of Ophthalmology, Gil Medical Center, Gachon University, Incheon, Republic of Korea.
Jong Min KimNune Eye Hospital, Seoul, Republic of Korea.
Yong Kyun ShinDepartment of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, #81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea.
Min Chae KangDepartment of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, #81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea.
Joon Kyo ChungDepartment of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, #81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea.
Chaeyeon LeeDepartment of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, #81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea.
Dongyoung LeeDepartment of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, #81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea.
Se Woong KangDepartment of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, #81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea.
Baek Hwan ChoMedical AI Research Center, Samsung Medical Center, #81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea. baekhwan.cho@samsung.com.
Sang Jin KimDepartment of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, #81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea. sangjin.kim.md@gmail.com.

Funding

Ministry of Science and ICT, South Korea NRF-2017M3A9E1064784
6 · The paper itself

Abstract

This study aimed to validate and evaluate deep learning (DL) models for screening of high myopia using spectral-domain optical coherence tomography (OCT). This retrospective cross-sectional study included 690 eyes in 492 patients with OCT images and axial length measurement. Eyes were divided into three groups based on axial length: a "normal group," a "high myopia group," and an "other retinal disease" group. The researchers trained and validated three DL models to classify the three groups based on horizontal and vertical OCT images of the 600 eyes. For evaluation, OCT images of 90 eyes were used. Diagnostic agreements of human doctors and DL models were analyzed. The area under the receiver operating characteristic curve of the three DL models was evaluated. Absolute agreement of retina specialists was 99.11% (range: 97.78-100%). Absolute agreement of the DL models with multiple-column model was 100.0% (ResNet 50), 90.0% (Inception V3), and 72.22% (VGG 16). Areas under the receiver operating characteristic curves of the DL models with multiple-column model were 0.99 (ResNet 50), 0.97 (Inception V3), and 0.86 (VGG 16). The DL model based on ResNet 50 showed comparable diagnostic performance with retinal specialists. The DL model using OCT images demonstrated reliable diagnostic performance to identify high myopia.

Indexed as

AdultAgedCross-Sectional StudiesDeep LearningEyeFemaleHumansImage Processing, Computer-AssistedIntraocular PressureMaleMiddle AgedMyopiaNerve FibersRepublic of KoreaRetinaRetinal Diseases

Identifiers

PMID34737335
PMCPMC8568935

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.