Evidence map›Paper›PMID 34737258›Full record

ArticleNature communications2021

Higher intake of whole grains and dietary fiber are associated with lower risk of liver cancer and chronic liver disease mortality.

Xing Liu, Wanshui Yang, Jessica L Petrick, Linda M Liao, Weibing Wang, Na He, Peter T Campbell, Zuo-Feng Zhang, Edward Giovannucci, Katherine A McGlynn and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 2 pooled it
9.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 2 syntheses or guidelines pooled it, 93 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 2 countries.

Xing LiuDepartment of Nutrition, T.H. Chan School of Public Health, Harvard University, Boston, MA, USA.
Wanshui YangChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-7365-2689
Jessica L PetrickSlone Epidemiology Center, Boston University, Boston, MA, USA.ORCID 0000-0001-6580-450X
Linda M LiaoDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.
Weibing WangDepartment of Epidemiology, School of Public Health, Fudan University, Shanghai, P.R. China.
Na HeDepartment of Epidemiology, School of Public Health, Fudan University, Shanghai, P.R. China.
Peter T CampbellBehavioral and Epidemiology Research Group, American Cancer Society, Atlanta, GA, USA.
Zuo-Feng ZhangDepartment of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, CA, USA.ORCID 0000-0002-4669-3995
Edward GiovannucciDepartment of Nutrition, T.H. Chan School of Public Health, Harvard University, Boston, MA, USA.
Katherine A McGlynnDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.
Xuehong ZhangDepartment of Nutrition, T.H. Chan School of Public Health, Harvard University, Boston, MA, USA. xuehong.zhang@channing.harvard.edu.ORCID 0000-0002-8260-8508
Brigham and Women's Hospital · USFudan University · CNNational Cancer Institute · USAmerican Cancer Society · USBoston University · USHarvard University · USUniversity of California, Los Angeles · US

Funding

Calcium and Colorectal Cancer: Gene-Environment Interactions and Molecular PathwaysK07CA188126 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI ZHANG, XUEHONG · 2015 to 2018
$576k
Proteomics Study of Non-viral Related Hepatocellular Carcinoma RiskR21CA238651 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI ZHANG, XUEHONG · 2020 to 2021
$477k
NCI NIH HHS K07 CA188126NCI NIH HHS R21 CA238651
6 · The paper itself

Abstract

The relationship between dietary factors and liver disease remains poorly understood. This study evaluated the associations of whole grain and dietary fiber intake with liver cancer risk and chronic liver disease mortality. The National Institutes of Health-American Association of Retired Persons Diet and Health Study cohort recruited 485, 717 retired U.S. participants in 1995-1996. Follow-up through 2011 identified 940 incident liver cancer cases and 993 deaths from chronic liver disease. Compared with the lowest, the highest quintile of whole grain intake was associated with lower liver cancer risk (Hazard ratio [HR]

Indexed as

Dietary FiberAgedEatingEdible GrainFemaleHumansLiver DiseasesLiver NeoplasmsMaleMiddle AgedProportional Hazards ModelsSurveys and QuestionnairesDietary Fiber

Identifiers

PMID34737258
PMCPMC8568891
OpenAlexW3209812026

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.