Evidence map›Paper›PMID 34737175›Full record

ArticlePediatrics2022

A School-Based SARS-CoV-2 Testing Program: Testing Uptake and Quarantine Length After In-School Exposures.

Angelique E Boutzoukas, Kanecia O Zimmerman, Tara K Mann, Ganga S Moorthy, Ashley Blakemore, Kathleen A McGann, Michael J Smith, Boen Nutting, Karen Kerley, M Alan Brookhart and 4 more

Abstract read
In one paragraph

Article in Pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. SARS-CoV-2 Screening Testing Programs for Safe In-person Learning in K-12 Schools.Journal of the Pediatric Infectious Diseases Society · 2023
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Angelique E BoutzoukasDepartments of Pediatrics.
Kanecia O ZimmermanDepartments of Pediatrics.
Tara K MannDuke Clinical Research Institute, School of Medicine, Duke University, Durham, North Carolina.
Ganga S MoorthyDepartments of Pediatrics.
Ashley BlakemoreDuke Clinical Research Institute, School of Medicine, Duke University, Durham, North Carolina.
Kathleen A McGannDepartments of Pediatrics.
Michael J SmithDepartments of Pediatrics.
Boen NuttingIredell-Statesville Schools, Statesville, North Carolina.
Karen KerleyIredell-Statesville Schools, Statesville, North Carolina.
M Alan BrookhartPopulation Health Sciences, School of Medicine, Duke University, Durham, North Carolina.
Laura EdwardsDuke Clinical Research Institute, School of Medicine, Duke University, Durham, North Carolina.
Zsolt RakDuke Clinical Research Institute, School of Medicine, Duke University, Durham, North Carolina.
Daniel K BenjaminDepartments of Pediatrics.
Ibukunoluwa C KaluDepartments of Pediatrics.

Funding

COVID-19 Supplement - Center for Innovative TRIals in ChilDrEN and AdulTs (TRIDENT)U24TR001608 · NCATS · DUKE UNIVERSITY · PI BENJAMIN, DANIEL K. · 2016 to 2022
$177.0M
RADx-UP SAY YES COVID Test Study (S4)U24MD016258 · NIMHD · DUKE UNIVERSITY · PI COHEN-WOLKOWIEZ, MICHAEL, DAVE, GAURAV J · 2020 to 2023
$116.7M
SARS-CoV-2 Screening and Diagnostic testing for return to K-12 schoolsOT2HD107559 · NICHD · DUKE UNIVERSITY · PI BENJAMIN, DANIEL K., ZIMMERMAN, KANECIA OBIE · 2021 to 2022
$5.0M
Support for Safe Return to in-Person School: COVID-19 Testing, Learning, and Consultation (School TLC)OT2HD107555 · NICHD · ICF MACRO, INC. · PI GOLDMAN, JENNIFER LYNN, KEENER MAST, DANA · 2021 to 2022
$5.0M
Project Safe Schools: Re-opening schools SAFELY for Native American youthOT2HD107543 · NICHD · JOHNS HOPKINS UNIVERSITY · PI BARLOW, MARY ALLISON, HAMMITT, LAURA · 2021 to 2022
$4.8M
COV-IDD: Testing for COVID-19 in high risk children with intellectual and developmental disabilitiesOT2HD107553 · NICHD · UNIVERSITY OF ROCHESTER · PI DEWHURST, STEPHEN, FOXE, JOHN J · 2021 to 2022
$4.0M
Using COVID-19 testing and risk communication strategies to accelerate students return to schoolOT2HD107544 · NICHD · UNIVERSITY OF WASHINGTON · PI KO, LINDA K. · 2021 to 2022
$4.0M
Assessing Testing Strategies for Safe Return to K-12 Schools in an Underserved PopulationOT2HD107557 · NICHD · WASHINGTON UNIVERSITY · PI NEWLAND, JASON · 2021 to 2022
$4.0M
ReSET: Restarting Safe Education and Testing for Children with Medical ComplexityOT2HD107558 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI COLLER, RYAN J, DEMURI, GREGORY P · 2021 to 2022
$3.0M
Unified Program for Therapeutics in Children (UPTiC)T32HD094671 · NICHD · DUKE UNIVERSITY · PI Ian J Davis, Kanecia Obie Zimmerman · 2019 to 2026
$2.9M
WUIDDRC and KKI Safe Return to SchoolOT2HD107556 · NICHD · WASHINGTON UNIVERSITY · PI GURNETT, CHRISTINA, KALB, LUTHER · 2021 to 2021
$2.7M
NCATS NIH HHS U24 TR001608NICHD NIH HHS HHSN275201000003CNICHD NIH HHS HHSN275201000003INICHD NIH HHS OT2 HD107543NICHD NIH HHS OT2 HD107544NICHD NIH HHS OT2 HD107553NICHD NIH HHS OT2 HD107555NICHD NIH HHS OT2 HD107556NICHD NIH HHS OT2 HD107557NICHD NIH HHS OT2 HD107558NICHD NIH HHS OT2 HD107559NICHD NIH HHS T32 HD094671NIMHD NIH HHS U24 MD016258
6 · The paper itself

Abstract

objectivesSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-related quarantines, which are required after close contact with infected individuals, have substantially disrupted in-person education for kindergarten through 12th grade (K-12) students. In recent recommendations, shortened durations of quarantine are allowed if a negative SARS-CoV-2 test result is obtained at 5 to 7 days postexposure, but access to testing remains limited. We hypothesized that providing access to in-school SARS-CoV-2 testing postexposure would increase testing and reduce missed school days.

methodsThis prospective cohort study was conducted in one large public K-12 school district in North Carolina and included 2 periods: preimplementation (March 15, 2021, to April 21, 2021) and postimplementation (April 22, 2021, to June 4, 2021), defined around initiation of an in-school SARS-CoV-2 testing program in which on-site access to testing is provided. Number of quarantined students and staff, testing uptake, test results, and number of missed school days were analyzed and compared between the preimplementation and postimplementation periods.

resultsTwenty-four schools, including 12 251 in-person learners, participated in the study. During preimplementation, 446 close contacts were quarantined for school-related exposures; 708 close contacts were quarantined postimplementation. Testing uptake after school-related exposures increased from 6% to 40% (95% confidence interval: 23% to 45%) after implementation, and 89% of tests were conducted in-school. After in-school testing implementation, close contacts missed ∼1.5 fewer days of school (95% confidence interval: -2 to -1).

conclusionsProviding access to in-school testing may be a worthwhile mechanism to increase testing uptake after in-school exposures and minimize missed days of in-person learning, thereby mitigating the pandemic's ongoing impact on children.

Indexed as

COVID-19 TestingQuarantineAdolescentChildChild, PreschoolCohort StudiesCOVID-19HumansNorth CarolinaSchool Health Services

Identifiers

PMID34737175
PMCPMC9647777

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.