Evidence map›Paper›PMID 34736538›Full record

ArticleJournal of eating disorders2021

Using individual networks to identify treatment targets for eating disorder treatment: a proof-of-concept study and initial data.

Cheri A Levinson, Rowan A Hunt, Ani C Keshishian, Mackenzie L Brown, Irina Vanzhula, Caroline Christian, Leigh C Brosof, Brenna M Williams

Erratum issued 3 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in Journal of eating disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 3 registered trials, which are not on this map. Cited by 48 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 2 pooled it
11.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04183894 nacompletednot on this map

Feasibility of Network-Informed Personalized Treatment for Eating Disorders

TypeinterventionalSponsorUniversity of LouisvilleRan2018 to 2023Enrolled59ConditionsEating Disorders, Eating Disorder SymptomArmsPersonalized Intervention
NCT05920720 nacompletednot on this mapstarted 2025, after this paper: background citation

Personalizing Disordered Eating Treatment Using Mobile Technology: Self-Guided, Personalized Treatment for Women

TypeinterventionalSponsorUniversity of LouisvilleRan2025 to 2026Enrolled20ConditionsDisordered EatingArmsSelf-guided Personalized Treatment
NCT06208605 narecruitingnot on this mapstarted 2024, after this paper: background citation

Innovations in Personalizing Treatment for Eating Disorders Using Idiographic Methods and the Impact of Personalization on Psychological, Physical, and Sociodemographic Outcomes

TypeinterventionalSponsorUniversity of LouisvilleRan2024 to 2029Enrolled320ConditionsEating DisordersArmsTransdiagnostic Network Informed Personalized Treatment, Enhanced Cognitive Behavioral Therapy for Eating Disorders
3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 2 syntheses or guidelines pooled it, 96 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Cheri A LevinsonDepartment of Psychological and Brain Sciences, University of Louisville, Life Sciences Building, Louisville, KY, 40292, USA. cheri.levinson@louisville.edu.
Rowan A HuntDepartment of Psychological and Brain Sciences, University of Louisville, Life Sciences Building, Louisville, KY, 40292, USA.
Ani C KeshishianDepartment of Psychological and Brain Sciences, University of Louisville, Life Sciences Building, Louisville, KY, 40292, USA.
Mackenzie L BrownDepartment of Psychological and Brain Sciences, University of Louisville, Life Sciences Building, Louisville, KY, 40292, USA.
Irina VanzhulaDepartment of Psychological and Brain Sciences, University of Louisville, Life Sciences Building, Louisville, KY, 40292, USA.
Caroline ChristianDepartment of Psychological and Brain Sciences, University of Louisville, Life Sciences Building, Louisville, KY, 40292, USA.
Leigh C BrosofDepartment of Psychological and Brain Sciences, University of Louisville, Life Sciences Building, Louisville, KY, 40292, USA.
Brenna M WilliamsDepartment of Psychological and Brain Sciences, University of Louisville, Life Sciences Building, Louisville, KY, 40292, USA.
University of Louisville · US

Funding

Innovations in Personalizing Treatment for Eating Disorders Using Idiographic Methods and the Impact of Personalization on Psychological, Physical, and Sociodemographic OutcomesDP2MH136495 · NIMH · UNIVERSITY OF LOUISVILLE · PI Cheri Alicia Levinson · 2023 to 2026
$2.6M
NIMH NIH HHS DP2 MH136495
6 · The paper itself

Abstract

backgroundEating disorders (EDs) are severe mental illnesses, with high morbidity, mortality, and societal burden. EDs are extremely heterogenous, and only 50% of patients currently respond to first-line treatments. Personalized and effective treatments for EDs are drastically needed.

methodsThe current study (N = 34 participants with an ED diagnosis collected throughout the United States) aimed to investigate best methods informing how to select personalized treatment targets utilizing idiographic network analysis, which could then be used for evidence based personalized treatment development. We present initial data collected via experience sampling (i.e., ecological momentary assessment) over the course of 15 days, 5 times a day (75 total measurement points) that were used to select treatment targets for a personalized treatment for EDs.

resultsOverall, we found that treatment targets were highly variable, with less than 50% of individuals endorsing central symptoms related to weight and shape, consistent with current treatment response rates for treatments designed to target those symptoms. We also found that different aspects of selection methods (e.g., number of items, type of centrality measure) impacted treatment target selection.

conclusionsWe discuss implications of these data, how to use idiographic network analysis to personalize treatment, and identify areas that need future research.

trial registrationClinicaltrials.gov, NCT04183894. Registered 3 December 2019-Retrospectively registered, https://clinicaltrials.gov/ct2/show/NCT04183894 . NCT04183894 (ClinicalTrials.gov identifier).

Indexed as

Eating disordersIdiographic modelingNetwork analysisPersonalized treatmentPrecision treatment

Identifiers

PMID34736538
PMCPMC8567590
OpenAlexW3209630959

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.