Evidence map›Paper›PMID 34736414›Full record

ArticleBMC microbiology2021

Molecular epidemiology of methicillin resistant Staphylococcus species in healthcare workers of a blood bank in the Brazilian Amazon.

Cristina Motta Ferreira, Roberto Alexandre Alves Barbosa Filho, Guilherme Motta Antunes Ferreira, Marcus Vinicius Guimarães de Lacerda, Cintia Mara Costa de Oliveira, Vanderson de Souza Sampaio, Lucyane Mendes Silva, Andreza Gomes Pascoal, William Antunes Ferreira

Open access · goldAbstract read
In one paragraph

Article in BMC microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Cristina Motta FerreiraFundação Hospitalar de Hematologia e Hemoterapia do Amazonas - HEMOAM, Manaus, Brazil. cris_motta_ferr@yahoo.com.br.
Roberto Alexandre Alves Barbosa FilhoUniversidade Federal do Amazonas - UFAM, Manaus, Brazil.
Guilherme Motta Antunes FerreiraFundação Hospitalar de Hematologia e Hemoterapia do Amazonas - HEMOAM, Manaus, Brazil.
Marcus Vinicius Guimarães de LacerdaFundação de Medicina Tropical Dr. Heitor Vieira Dourado - FMT-HVD, Manaus, Brazil.
Cintia Mara Costa de OliveiraUniversidade Federal do Amazonas - UFAM, Manaus, Brazil.
Vanderson de Souza SampaioUniversidade do Estado do Amazonas - Programa de Pós-Graduação em Medicina Tropical, Manaus, Brazil.
Lucyane Mendes SilvaFundação Hospitalar de Hematologia e Hemoterapia do Amazonas - HEMOAM, Manaus, Brazil.
Andreza Gomes PascoalFundação Hospitalar de Hematologia e Hemoterapia do Amazonas - HEMOAM, Manaus, Brazil.
William Antunes FerreiraFundação de Dermatologia Tropical e Venereologia Alfredo da Matta - FUAM, Manaus, Brazil.
Fundação de Medicina Tropical · BRFundação Hospitalar de Hematologia e Hemoterapia do Amazonas · BRUniversidade do Estado do Amazonas · BRUniversidade Federal do Amazonas · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHealthcare workers are susceptible to colonization by multiresistant bacteria, which can increase the risk of outbreaks.

methodsSamples were collected from the nasopharynx, hands, and lab coats of healthcare workers. The phenotypic identification was carried out using a VITEK®2 rapid test system. PCR tests for the mecA gene and the sequencing of the amplicons were performed. Staphylococcus epidermidis and Staphylococcus aureus phylogenies were reconstructed using the Bayesian inference.

resultsA total of 225 healthcare workers participated in this study. Of these, 21.3% were male and 78.7% female. S. epidermidis and S.aureus showed high levels of resistance to penicillin, ampicillin, erythromycin, tetracycline and cefoxitin. The prevalence of methicillin resistant S. aureus was 3.16% and methicillin resistant S. epidermidis was 100%. Multilocus sequence typing identified 23 new S. epidermidis sequence types, and one new allele and sequence type for S. aureus. The frequency of methicillin-resistant S. epidermidis in nursing and hemotherapy technicians as a percentage of the total number of healthcare workers was 5.8-3.1%, while the frequency of methicillin resistant S. aureus in hemotherapy technicians and biomedics, as a percentage of the total number of healthcare workers was 4.2-8.9%%.

conclusionsThe healthcare workers at the city's blood bank, even when taking the necessary care with their hands, body and clothes, harbour methicillin-resistant S. aureus and S. epidermidis sequence types, which, as a potential source of multidrug resistant bacteria, can contribute to nosocomial infections among hematological patients.

Indexed as

AdultAnti-Bacterial AgentsBlood BanksBrazilCarrier StateFemaleHandHealth PersonnelHumansMaleMethicillin ResistanceMethicillin-Resistant Staphylococcus aureusMicrobial Sensitivity TestsMiddle AgedMolecular EpidemiologyNasopharynxAnti-Bacterial AgentsCloneMultirresistanceOxacillinS. epidermidisST

Identifiers

PMID34736414
PMCPMC8567558
OpenAlexW3208245436

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.