Evidence map›Paper›PMID 34736316›Full record

ArticleObstetrics & gynecology science2022

Clinical manifestations and pregnancy outcomes of COVID-19 in indonesian referral hospital in central pandemic area.

Muhammad Ilham Aldika Akbar, Khanisyah Erza Gumilar, Rino Andriya, Manggala Pasca Wardhana, Pungky Mulawardhana, Jimmy Yanuar Anas, Ernawati, Muhammad Ardian Cahya Laksana, Gustaaf Dekker

Open access · diamondAbstract read
In one paragraph

Article in Obstetrics & gynecology science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Risk factors and outcomes of critically ill pregnant COVID-19 patients: Experience from the first and second waves of the pandemic.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2025
    Article
  3. Article
  4. Maternal Characteristics and Outcomes Affected by COVID-19 Pandemic in Indonesia.Journal of obstetrics and gynaecology of India · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Muhammad Ilham Aldika AkbarDepartment of Obstetrics and Gynaecology, Airlangga University Hospital, Universitas Airlangga Faculty of Medicine, Surabaya, Indonesia.
Khanisyah Erza GumilarDepartment of Obstetrics and Gynaecology, Airlangga University Hospital, Universitas Airlangga Faculty of Medicine, Surabaya, Indonesia.
Rino AndriyaDepartment of Obstetrics and Gynaecology, Airlangga University Hospital, Universitas Airlangga Faculty of Medicine, Surabaya, Indonesia.
Manggala Pasca WardhanaDepartment of Obstetrics and Gynaecology, Faculty of Medicine Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.
Pungky MulawardhanaDepartment of Obstetrics and Gynaecology, Airlangga University Hospital, Universitas Airlangga Faculty of Medicine, Surabaya, Indonesia.
Jimmy Yanuar AnasDepartment of Obstetrics and Gynaecology, Airlangga University Hospital, Universitas Airlangga Faculty of Medicine, Surabaya, Indonesia.
ErnawatiDepartment of Obstetrics and Gynaecology, Faculty of Medicine Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.
Muhammad Ardian Cahya LaksanaDepartment of Obstetrics and Gynaecology, Faculty of Medicine Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.
Gustaaf DekkerDepartment of Obstetrics and Gynaecology, Airlangga University Hospital, Universitas Airlangga Faculty of Medicine, Surabaya, Indonesia.
Airlangga University · IDUniversitas Dr. Soetomo · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectives Data on the clinical manifestations and pregnancy outcomes of pregnant women with COVID-19 are limited, particularly in developing countries. The aim of this study was to analyze the clinical manifestations and pregnancy outcomes in COVID-19 maternal cases in a large referral hospital in Indonesia.

methodsThis study used a prospective cohort design and included all pregnant women with suspected COVID-19. Subjects were divided into COVID-19 and non-COVID-19 groups based on the results of real-time polymerase chain reaction (RT-PCR) for severe acute respiratory syndrome coronavirus 2. Clinical characteristics, laboratory results, and pregnancy outcomes were compared between the two groups.

resultsOf the 141 suspected maternal cases, 62 cases were COVID-19-confirmed (43.9%), while 79 suspected cases were negative (56.1%). The clinical manifestations and laboratory findings between the two groups were not significantly different (P>0.05). However, the maternal mortality directly caused by COVID-19 was significantly higher than that in the non-COVID-19 group (8.3% vs. 1.3%; P=0.044; odd ratio, 6.91; 95% confidence interval, 0.79-60.81).

conclusionThe clinical manifestations and laboratory results of suspected pregnant women with positive and negative RT-PCR COVID-19 results were similar. However, within the Indonesian setting, COVID-19 significantly increases the risk of maternal death through both direct and indirect factors.

Indexed as

Maternal healthMaternal mortalityPregnancy

Identifiers

PMID34736316
PMCPMC8784935
OpenAlexW3177250357

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.