Evidence map›Paper›PMID 34736114›Full record

ArticleBiosensors & bioelectronics2022

Aptasensing nucleocapsid protein on nanodiamond assembled gold interdigitated electrodes for impedimetric SARS-CoV-2 infectious disease assessment.

Santheraleka Ramanathan, Subash C B Gopinath, Zool Hilmi Ismail, M K Md Arshad, Prabakaran Poopalan

Open access · greenAbstract read
In one paragraph

Article in Biosensors & bioelectronics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 81 citations in OpenAlex.

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  10. Aptamers: precision tools for diagnosing and treating infectious diseases.Frontiers in cellular and infection microbiology · 2024
    Review
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  20. A novel photoelectrochemical immunosensor based on TiOMicrochemical journal : devoted to the application of microtechniques in all branches of science · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Santheraleka RamanathanInstitute of Nano Electronic Engineering, Universiti Malaysia Perlis (UniMAP), 01000, Kangar, Perlis, Malaysia.
Subash C B GopinathInstitute of Nano Electronic Engineering, Universiti Malaysia Perlis (UniMAP), 01000, Kangar, Perlis, Malaysia; Faculty of Chemical Engineering Technology, Universiti Malaysia Perlis (UniMAP), 02600, Arau, Perlis, Malaysia. Electronic address: subash@unimap.edu.my.
Zool Hilmi IsmailCentre for Artificial Intelligence and Robotics, Universiti Teknologi Malaysia, Jalan Sultan Yahya Petra, 54100, Kuala Lumpur, Malaysia. Electronic address: zool@utm.my.
M K Md ArshadInstitute of Nano Electronic Engineering, Universiti Malaysia Perlis (UniMAP), 01000, Kangar, Perlis, Malaysia; Faculty of Electronic Engineering Technology, Universiti Malaysia Perlis (UniMAP), 02600, Arau, Pauh Putra, Perlis, Malaysia.
Prabakaran PoopalanFaculty of Electronic Engineering Technology, Universiti Malaysia Perlis (UniMAP), 02600, Arau, Pauh Putra, Perlis, Malaysia.
Universiti Malaysia Perlis · MYUniversity of Technology Malaysia · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In an aim of developing portable biosensor for SARS-CoV-2 pandemic, which facilitates the point-of-care aptasensing, a strategy using 10 μm gap-sized gold interdigitated electrode (AuIDE) is presented. The silane-modified AuIDE surface was deposited with ∼20 nm diamond and enhanced the detection of SARS-CoV-2 nucleocapsid protein (NCP). The characteristics of chemically modified diamond were evidenced by structural analyses, revealing the cubic crystalline nature at (220) and (111) planes as observed by XRD. XPS analysis denotes a strong interaction of carbon element, composed ∼95% as seen in EDS analysis. The C-C, CC, CO, CN functional groups were well-refuted from XPS spectra of carbon and oxygen elements in diamond. The interrelation between elements through FTIR analysis indicates major intrinsic bondings at 2687-2031 cm

Indexed as

Aptamers, NucleotideBiosensing TechniquesCommunicable DiseasesCOVID-19NanodiamondsElectrochemical TechniquesElectrodesGoldHumansLimit of DetectionNucleocapsid ProteinsSARS-CoV-2Aptamers, NucleotideGoldNanodiamondsNucleocapsid ProteinsBiomarkerBiosensorCorona virusCOVID-19PandemicRespiratory virus

Identifiers

PMID34736114
PMCPMC8550887
OpenAlexW3211252372

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.