Evidence map›Paper›PMID 34736095›Full record

SynthesisGait & posture2022

Relationship between ankle function and walking ability for children and young adults with cerebral palsy: A systematic review of deficits and targeted interventions.

Benjamin C Conner, Nushka M Remec, Cassidy M Michaels, Chase W Wallace, Emily Andrisevic, Zachary F Lerner

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in Gait & posture, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Advances on mechanical designs for assistive ankle-foot orthoses.Frontiers in bioengineering and biotechnology · 2023
    Review
  10. Article
  11. Article
  12. Article
  13. Ankle Exoskeleton Assistance Increases Six-Minute Walk Test Performance in Cerebral Palsy.IEEE open journal of engineering in medicine and biology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Benjamin C ConnerCollege of Medicine - Phoenix, University of Arizona, Phoenix, AZ, USA.
Nushka M RemecPhoenix Children's Hospital, Phoenix, AZ, USA.
Cassidy M MichaelsSchool of Biological and Health Systems Engineering, Arizona State University, Tempe, AZ, USA.
Chase W WallaceSchool of Biological and Health Systems Engineering, Arizona State University, Tempe, AZ, USA.
Emily AndrisevicPhoenix Children's Hospital, Phoenix, AZ, USA.
Zachary F LernerCollege of Medicine - Phoenix, University of Arizona, Phoenix, AZ, USA; Department of Mechanical Engineering, Northern Arizona University, 15600 S McConnell Drive, NAU EGR Bldg 69, Flagstaff, AZ 86011, USA. Electronic address: Zachary.Lerner@nau.edu.
Arizona State University · USPhoenix Children's Hospital · USUniversity of Arizona · US

Funding

Wearable Ankle Assistance to Improve Walking Economy in Children with Cerebral PalsyR15HD099664 · NICHD · NORTHERN ARIZONA UNIVERSITY · PI LERNER, ZACHARY FOREST · 2019 to 2019
$424k
Investigation of the neuromuscular response and training effects of wearable adaptive resistance in children with cerebral palsyF30HD103318 · NICHD · UNIVERSITY OF ARIZONA · PI CONNER, BENJAMIN CHARLES · 2021 to 2024
$183k
NICHD NIH HHS F30 HD103318NICHD NIH HHS R15 HD099664
6 · The paper itself

Abstract

backgroundA primary goal of treatment for children with cerebral palsy is improved walking ability to allow for a more active and independent lifestyle. With the importance of ankle function to walking ability, and the deficits in ankle function associated with cerebral palsy, there is good rationale for targeting this joint in an effort to improve walking ability for this population. RESEARCH QUESTION: How do deficits and targeted interventions of the ankle joint influence walking ability in children with cerebral palsy?

methodsA specific search criteria was used to identify articles that either (1) provided information on the relationship between ankle function and walking ability or (2) investigated the effect of a targeted ankle intervention on walking ability in cerebral palsy. PubMed, Embase, CINAHL, and Web of Science databases were searched from 1980-April, 2020. Resulting citations were compared against a prospective set of inclusion and exclusion criteria. Data relevant to the original research question was extracted, and the level of evidence for each intervention study was scored. Interpretation was focused on specific, pre-determined mobility measures.

resultsSixty-one citations met all criteria for data extraction, six of which were observational, and fifty-five of which were interventional. Level of evidence ranged from 2 to 4. Self-selected walking speed was the most common measure of walking ability, while physical activity level was the least common. SIGNIFICANCE: Ankle function is an important contributor to the walking ability of children with cerebral palsy, and most interventions targeting the ankle seem to demonstrate a benefit on walking ability, but future higher-powered and/or controlled studies are necessary to confirm these findings.

Indexed as

Cerebral PalsyAnkleAnkle JointChildHumansProspective StudiesWalkingYoung AdultAnkle jointCerebral palsySystematic reviewWalking ability

Identifiers

PMID34736095
PMCPMC8671343
OpenAlexW3209447386

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.