Evidence map›Paper›PMID 34735954›Full record

ArticleEnvironment international2022

Wastewater surveillance demonstrates high predictive value for COVID-19 infection on board repatriation flights to Australia.

Warish Ahmed, Aaron Bivins, Stuart L Simpson, Paul M Bertsch, John Ehret, Ian Hosegood, Suzanne S Metcalfe, Wendy J M Smith, Kevin V Thomas, Josh Tynan and 1 more

Open access · goldAbstract read
In one paragraph

Article in Environment international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 2 pooled it
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 67 citations in OpenAlex.

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  14. Structured Ethical Review for Wastewater-Based Testing.medRxiv : the preprint server for health sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Warish AhmedCSIRO Land and Water, Ecosciences Precinct, 41 Boggo Road, Brisbane, QLD 4102, Australia. Electronic address: Warish.Ahmed@csiro.au.
Aaron BivinsDepartment of Civil & Environmental Engineering & Earth Science, University of Notre Dame, 156 Fitzpatrick Hall, Notre Dame, IN 46556, USA.
Stuart L SimpsonCSIRO Land and Water, Lucas Heights, NSW 2234, Australia.
Paul M BertschCSIRO Land and Water, Ecosciences Precinct, 41 Boggo Road, Brisbane, QLD 4102, Australia.
John EhretQantas Airways Limited, 10 Bourke Rd Mascot, 2020, NSW, Australia.
Ian HosegoodQantas Airways Limited, 10 Bourke Rd Mascot, 2020, NSW, Australia.
Suzanne S MetcalfeCSIRO Land and Water, Ecosciences Precinct, 41 Boggo Road, Brisbane, QLD 4102, Australia.
Wendy J M SmithCSIRO Land and Water, Ecosciences Precinct, 41 Boggo Road, Brisbane, QLD 4102, Australia.
Kevin V ThomasQueensland Alliance for Environmental Health Sciences (QAEHS), The University of Queensland, 20 Cornwall Street, Woolloongabba, QLD 4103, Australia.
Josh TynanQueensland Alliance for Environmental Health Sciences (QAEHS), The University of Queensland, 20 Cornwall Street, Woolloongabba, QLD 4103, Australia.
Jochen F MuellerQueensland Alliance for Environmental Health Sciences (QAEHS), The University of Queensland, 20 Cornwall Street, Woolloongabba, QLD 4103, Australia.
CSIRO Land and Water · AUUniversity of Queensland · AUUniversity of Notre Dame · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Controlling importation and transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from overseas travelers is essential for countries, such as Australia, New Zealand, and other island nations, that have adopted a suppression strategy to manage very low community transmission. Wastewater surveillance of SARS-CoV-2 RNA has emerged as a promising tool employed in public health response in many countries globally. This study aimed to establish whether the surveillance of aircraft wastewater can be used to provide an additional layer of information to augment individual clinical testing. Wastewater from 37 long-haul flights chartered to repatriate Australians was tested for the presence of SARS-CoV-2 RNA. Children 5 years or older on these flights tested negative for coronavirus disease 19 (COVID-19) (deep nasal and oropharyngeal reverse-transcription (RT)-PCR swab) 48 h before departure. All passengers underwent mandatory quarantine for 14-day post arrival in Howard Springs, NT, Australia. Wastewater from 24 (64.9 %) of the 37 flights tested positive for SARS-CoV-2 RNA. During the 14 day mandatory quarantine, clinical testing identified 112 cases of COVID-19. Surveillance for SARS-CoV-2 RNA in repatriation flight wastewater using pooled results from three RT-qPCR assays demonstrated a positive predictive value (PPV) of 87.5 %, a negative predictive value (NPV) of 76.9 % and 83.7% accuracy for COVID-19 cases during the post-arrival 14-day quarantine period. The study successfully demonstrates that the surveillance of wastewater from aircraft for SARS-CoV-2 can provide an additional and effective tool for informing the management of returning overseas travelers and for monitoring the importation of SARS CoV-2 and other clinically significant pathogens.

Indexed as

COVID-19AustraliaChildHumansReal-Time Polymerase Chain ReactionRNA, ViralSARS-CoV-2WastewaterWastewater-Based Epidemiological MonitoringRNA, ViralWastewaterAircraftCOVID-19Enveloped virusesHuman health risksSARS-CoV-2Wastewater surveillance

Identifiers

PMID34735954
PMCPMC8514683
OpenAlexW3206293259

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.