ArticleJournal of stroke and cerebrovascular diseases : the official journal of National Stroke Association2022
Shortening Door-to-Needle Time by Multidisciplinary Collaboration and Workflow Optimization During the COVID-19 Pandemic.
Article in Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Bridging therapy improves functional outcomes and reduces 90-day mortality compared with direct endovascular thrombectomy in patients with acute posterior ischemic stroke: a systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Pooled it
- Efficacy and safety of recanalization therapy for acute ischemic stroke with COVID-19: A systematic review and meta-analysis.Frontiers in neurology · 2022Pooled it
- Observational
- Article
- Association Between Sociodemographic Disparities and Door to Computerized Tomography Time in Patients with Acute Ischemic Stroke Across COVID-19 Periods in the Emergency Department: A Multi-Center Cohort Study.Medical sciences (Basel, Switzerland) · 2025Article
- Impact of COVID-19 pandemic on acute stroke care in a tertiary stroke centre.Scientific reports · 2024Article
- Application of multidisciplinaryWorld journal of emergency medicine · 2024Article
- The Impact of Pandemic-Driven Care Redesign on Hospital Efficiency.Risk management and healthcare policy · 2024Review
- Impact of in-hospital COVID-19 quarantine policy changes on quality of acute stroke care: a single center experience.Frontiers in neurology · 2024Article
- Intravenous thrombolysis for acute ischemic stroke during two COVID-19 outbreaks in China: Wuhan pandemic and Beijing pandemic.BMC neurology · 2023Article
- The Impact of COVID-19 Pandemic Lockdown on Emergency Department Visits in a Tertiary Hospital.Risk management and healthcare policy · 2023Article
- 7-Day National Institutes of Health Stroke Scale as a surrogate marker predicting ischemic stroke patients' outcome following endovascular therapy.Translational neuroscience · 2023Article
- Post-ASPECTS and Post-PC-ASPECTS Predict the Outcome of Anterior and Posterior Ischemic Stroke Following Thrombectomy.Risk management and healthcare policy · 2023Article
- Observational
- Predictors of failure of early neurological improvement in early time window following endovascular thrombectomy: a multi-center study.Frontiers in neurology · 2023Article
- Predictors of futile recanalization after endovascular treatment in acute ischemic stroke: a multi-center study.Frontiers in neuroscience · 2023Article
- Coronavirus disease 2019 and acute cerebrovascular events: a comprehensive overview.Frontiers in neurology · 2023Review
- Radio frequency identification technology reduce intravenous thrombolysis time in acute ischemic stroke.PloS one · 2023Article
- Impact of Thrombolysis Time Metrics When Participating in National Stroke Center Construction Project.Journal of multidisciplinary healthcare · 2023Article
- Shortening door-to-puncture time and improving patient outcome with workflow optimization in patients with acute ischemic stroke associated with large vessel occlusion.BMC emergency medicine · 2022Article
Corrections and comments
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Authors and funding
14 authors at 6 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis study aims to evaluate shortening door-to-needle time of intravenous recombinant tissue plasminogen activator of acute ischemic stroke patients by multidisciplinary collaboration and workflow optimization based on our hospital resources. MATERIALS AND
methodsWe included patients undergoing thrombolysis with intravenous recombinant tissue plasminogen activator from January 1, 2018, to September 30, 2020. Patients were divided into pre- (January 1, 2018, to December 31, 2019) and post-intervention groups (January 1, 2020, to September 31, 2020). We conducted multi-department collaboration and process optimization by implementing 16 different measures in prehospital, in-hospital, and post-acute feedback stages for acute ischemic stroke patients treated with intravenous thrombolysis. A comparison of outcomes between both groups was analyzed.
resultsTwo hundred and sixty-three patients received intravenous recombinant tissue plasminogen activator in our hospital during the study period, with 128 and 135 patients receiving treatment in the pre-intervention and post-intervention groups, respectively. The median (interquartile range) door-to-needle time decreased significantly from 57.0 (45.3-77.8) min to 37.0 (29.0-49.0) min. Door-to-needle time was shortened to 32 min in the post-intervention period in the 3rd quarter of 2020. The door-to-needle times at the metrics of ≤ 30 min, ≤ 45 min, ≤ 60 min improved considerably, and the DNT> 60 min metric exhibited a significant reduction.
conclusionsA multidisciplinary collaboration and continuous process optimization can result in overall shortened door-to-needle despite the challenges incurred by the COVID-19 pandemic.
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