ArticleCurrent biology : CB2021
Identification of the sex-determining factor in the liverwort Marchantia polymorpha reveals unique evolution of sex chromosomes in a haploid system.
Article in Current biology : CB, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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39 citing papers in PubMed, 73 citations in OpenAlex.
- A key role for S-nitrosylation in immune regulation and development in the liverwort Marchantia polymorpha.Journal of experimental botany · 2026Article
- Multiomics analyses of mutants for Marchantia polymorpha FERONIA and MARIS reveal a link between cell wall integrity and abscisic acid responses.Plant & cell physiology · 2026Article
- Causes and consequences of sex-chromosome turnovers in Diptera.Evolution letters · 2026Article
- Genome assemblies of the liverwort Blasia pusilla uncover a well-defined pseudoautosomal region on homomorphic UV sex chromosomes.Genome biology · 2026Article
- MarpolBase: genome database for Marchantia polymorpha featuring high quality reference genome sequences.Plant & cell physiology · 2026Article
- Origin and evolutionary trajectories of brown algal sex chromosomes.Nature ecology & evolution · 2025Article
- Structural and evolutionary features of red algal UV sex chromosomes.Genome biology · 2025Article
- Evolutionary history of sex and accessory chromosomes in hornworts.The New phytologist · 2025Article
- The Tree of Sex consortium: a global initiative for studying the evolution of reproduction in eukaryotes.Journal of evolutionary biology · 2025Article
- Growth phase diets diminish histone acetyltransferase Gcn5 function and shorten lifespan of Drosophila males.EMBO reports · 2025Article
- A genome assembly for the California endemic liverwort Calasterella californica.The Journal of heredity · 2025Article
- Evidence for evolution of a new sex chromosome within the haploid-dominant Marchantiales plant lineage.Journal of integrative plant biology · 2025Article
- Sex chromosome evolution in haploid plants: Microchromosomes, disappearing chromosomes, and giant chromosomes.Proceedings of the National Academy of Sciences of the United States of America · 2025Review
- Evolution of sexual systems and regressive evolution in Riccia.The New phytologist · 2025Article
- Cephalopod sex determination and its ancient evolutionary origin.Current biology : CB · 2025Article
- Pan-phylum genomes of hornworts reveal conserved autosomes but dynamic accessory and sex chromosomes.Nature plants · 2025Article
- The transcription factor PpRKD evokes female developmental fate in the sexual reproductive organs of Physcomitrium patens.The New phytologist · 2025Article
- Genome-wide characterization of BPC transcription factors in pear and functional validation ofFrontiers in plant science · 2025Article
- The Role of Female and Male Genes in Regulating Pollen Tube Guidance in Flowering Plants.Genes · 2024Review
- Why should we study plant sex chromosomes?The Plant cell · 2024Review
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24 authors at 8 institutions in 4 countries.
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Abstract
Sex determination is a central process for sexual reproduction and is often regulated by a sex determinant encoded on a sex chromosome. Rules that govern the evolution of sex chromosomes via specialization and degeneration following the evolution of a sex determinant have been well studied in diploid organisms. However, distinct predictions apply to sex chromosomes in organisms where sex is determined in the haploid phase of the life cycle: both sex chromosomes, female U and male V, are expected to maintain their gene functions, even though both are non-recombining. This is in contrast to the X-Y (or Z-W) asymmetry and Y (W) chromosome degeneration in XY (ZW) systems of diploids. Here, we provide evidence that sex chromosomes diverged early during the evolution of haploid liverworts and identify the sex determinant on the Marchantia polymorpha U chromosome. This gene, Feminizer, encodes a member of the plant-specific BASIC PENTACYSTEINE transcription factor family. It triggers female differentiation via regulation of the autosomal sex-determining locus of FEMALE GAMETOPHYTE MYB and SUPPRESSOR OF FEMINIZATION. Phylogenetic analyses of Feminizer and other sex chromosome genes indicate dimorphic sex chromosomes had already been established 430 mya in the ancestral liverwort. Feminizer also plays a role in reproductive induction that is shared with its gametolog on the V chromosome, suggesting an ancestral function, distinct from sex determination, was retained by the gametologs. This implies ancestral functions can be preserved after the acquisition of a sex determination mechanism during the evolution of a dominant haploid sex chromosome system.
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