Evidence map›Paper›PMID 34735288›Full record

ArticleThe CRISPR journal2021

Temperature-Inducible Precision-Guided Sterile Insect Technique.

Nikolay P Kandul, Junru Liu, Omar S Akbari

Open access · greenAbstract read
In one paragraph

Article in The CRISPR journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Review
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  7. Article
  8. Differential elimination of marked sex chromosomes enables production of nontransgenic male mosquitoes in a single strain.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Eliminating malaria vectors with precision-guided sterile males.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  13. Article
  14. Review
  15. Review
  16. Targeting Sex Determination to Suppress Mosquito Populations.bioRxiv : the preprint server for biology · 2023
    Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Nikolay P KandulDivision of Biological Sciences, Section of Cell and Developmental Biology, University of California, San Diego, La Jolla, California, USA.
Junru LiuDivision of Biological Sciences, Section of Cell and Developmental Biology, University of California, San Diego, La Jolla, California, USA.
Omar S AkbariDivision of Biological Sciences, Section of Cell and Developmental Biology, University of California, San Diego, La Jolla, California, USA.
University of California San Diego · US

Funding

Precision guided SIT for the control of vector-borne diseaseR01AI151004 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI AKBARI, OMAR SULTAN · 2020 to 2024
$2.3M
NIAID NIH HHS R01 AI151004
6 · The paper itself

Abstract

Releases of sterile males are the gold standard for many insect population control programs, and precise sex sorting to remove females prior to male releases is essential to the success of these operations. To advance traditional methods for scaling the generation of sterile males, we previously described a CRISPR-mediated precision-guided sterile insect technique (pgSIT), in which Cas9 and gRNA strains are genetically crossed to generate sterile males for mass release. While effective at generating F

Indexed as

Drosophila melanogasterGene EditingAnimalsCRISPR-Cas SystemsFemaleMaleRNA, Guide, CRISPR-Cas SystemsTemperatureRNA, Guide, CRISPR-Cas Systems

Identifiers

PMID34735288
PMCPMC8742271
OpenAlexW3208466463

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.