Evidence map›Paper›PMID 34735185›Full record

ArticleJournal of experimental psychology. General2022

Discriminating memory disordered patients from controls using diffusion model parameters from recognition memory.

Roger Ratcliff, Douglas W Scharre, Gail McKoon

Abstract read
In one paragraph

Article in Journal of experimental psychology. General, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. From symptom-based heterogeneity to mechanism-based profiling in youth ADHD: the promise of computational psychiatry.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Roger RatcliffDepartment of Psychology, Ohio State University.ORCID 0000-0001-9657-0814
Douglas W ScharreCenter for Cognitive and Memory Disorders, Ohio State University.ORCID 0000-0001-8622-3923
Gail McKoonDepartment of Psychology, Ohio State University.ORCID 0000-0002-7176-2235

Funding

Toward using comprehensive decision-making models in neuropsychological testingR01AG041176 · NIA · OHIO STATE UNIVERSITY · PI MCKOON, GAIL A, RATCLIFF, ROGER · 2012 to 2021
$3.8M
Decision Making on Continuous Scales in Aging and Alzheimers DiseaseR01AG057841 · NIA · OHIO STATE UNIVERSITY · PI MCKOON, GAIL A, RATCLIFF, ROGER · 2020 to 2024
$2.5M
NIA NIH HHSNIA NIH HHS R01 AG041176NIA NIH HHS R01 AG057841
6 · The paper itself

Abstract

One hundred and five memory disordered (MD) patients and 57 controls were tested on item recognition memory and lexical decision tasks, and diffusion model analyses were conducted on accuracy and response time distributions for correct and error responses. The diffusion model fit the data well for the MD patients and control subjects, the results replicated earlier studies with young and older adults, and individual differences were consistent between the item recognition and lexical decision tasks. In the diffusion model analysis, MD patients had lower drift rates (with mild Alzheimer's [AD] patients lower than mild cognitive impairment [MCI] patients) as well as wider boundaries and longer nondecision times. These data and results were used in a series of studies to examine how well MD patients could be discriminated from controls using machine-learning techniques, linear discriminant analysis, logistic regression, and support vector machines (all of which produced similar results). There was about 83% accuracy in separating MD from controls, and within the MD group, AD patients had about 90% accuracy and MCI patients had about 68% accuracy (controls had about 90% accuracy). These methods might offer an adjunct to traditional clinical diagnosis. Limitations are noted including difficulties in obtaining a matched group of control subjects as well as the possibility of misdiagnosis of MD patients. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

Indexed as

Cognitive DysfunctionAgedHumansLogistic ModelsMachine LearningReaction TimeRecognition, Psychology

Identifiers

PMID34735185
PMCPMC9065216

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.