Evidence map›Paper›PMID 34734691›Full record

ArticleACS chemical biology2021

Photoredox-Catalyzed Decarboxylative

Le Zhang, Brendan M Floyd, Maheshwerreddy Chilamari, James Mapes, Jagannath Swaminathan, Steven Bloom, Edward M Marcotte, Eric V Anslyn

Open access · greenAbstract read
In one paragraph

Article in ACS chemical biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Article
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  4. Article
  5. Article
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  7. Article
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  9. Protein Sequencing, One Molecule at a Time.Annual review of biophysics · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Le ZhangDepartment of Chemistry, The University of Texas at Austin, Austin, Texas 78712, United States.
Brendan M FloydDepartment of Molecular Biosciences, Center for Systems and Synthetic Biology, The University of Texas at Austin, Austin, Texas 78712, United States.ORCID 0000-0001-7412-0492
Maheshwerreddy ChilamariSchool of Pharmacy - Medicinal Chemistry, University of Kansas, Lawrence, Kansas 66045-7572, United States.
James MapesErisyon, Inc., Austin, Texas 78701, United States.
Jagannath SwaminathanDepartment of Molecular Biosciences, Center for Systems and Synthetic Biology, The University of Texas at Austin, Austin, Texas 78712, United States.
Steven BloomSchool of Pharmacy - Medicinal Chemistry, University of Kansas, Lawrence, Kansas 66045-7572, United States.ORCID 0000-0002-4205-4459
Edward M MarcotteDepartment of Molecular Biosciences, Center for Systems and Synthetic Biology, The University of Texas at Austin, Austin, Texas 78712, United States.ORCID 0000-0001-8808-180X
Eric V AnslynDepartment of Chemistry, The University of Texas at Austin, Austin, Texas 78712, United States.ORCID 0000-0002-5137-8797
The University of Texas at Austin · USUniversity of Kansas · US

Funding

Mapping the CPLANE interactome, an extensive protein interaction network underlying human ciliopathiesR01HD085901 · NICHD · UNIVERSITY OF TEXAS AT AUSTIN · PI EDWARD M MARCOTTE, John B Wallingford · 2016 to 2026
$6.2M
Proteomics and model organism humanization to decode human geneticsR35GM122480 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI EDWARD M MARCOTTE · 2017 to 2026
$5.4M
Mapping the blood cell protein complexosomeR01DK110520 · NIDDK · UNIVERSITY OF TEXAS AT AUSTIN · PI EMILI, ANDREW, MARCOTTE, EDWARD M · 2016 to 2018
$727k
NICHD NIH HHS R01 HD085901NIDDK NIH HHS R01 DK110520NIGMS NIH HHS R35 GM122480
6 · The paper itself

Abstract

Methods for the selective labeling of biogenic functional groups on peptides are being developed and used in the workflow of both current and emerging proteomics technologies, such as single-molecule fluorosequencing. To achieve successful labeling with any one method requires that the peptide fragments contain the functional group for which labeling chemistry is designed. In practice, only two functional groups are present in every peptide fragment regardless of the protein cleavage site, namely, an

Indexed as

AlkylationAmino AcidsAngiotensinsCatalysisDecarboxylationHumansOxidation-ReductionPeptidesPhotochemical ProcessesProteomicsSingle Molecule ImagingAmino AcidsAngiotensinsPeptides

Identifiers

PMID34734691
PMCPMC9006664
OpenAlexW3210706620

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.