Evidence map›Paper›PMID 34734351›Full record

ArticleJournal of cardiovascular translational research2022

Histamine Deficiency Promotes Myofibroblasts Transformation from HDC-Expressing CD11b

Baoling Zhu, Xiaowei Zhu, Xiangfei Wang, Jian Wu, Suling Ding, Weiwei Zhang, Yunzeng Zou, Junbo Ge, Xiangdong Yang

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of cardiovascular translational research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Baoling Zhu *Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.
Xiaowei Zhu *Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.
Xiangfei Wang *Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.
Jian WuShanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China. wu.jian@zs-hospital.sh.cn.
Suling DingShanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.
Weiwei ZhangShanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.
Yunzeng ZouShanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.
Junbo GeShanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.
Xiangdong YangShanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China. yang.xiangdong@zs-hospital.sh.cn.ORCID 0000-0002-4201-7017
Sun Yat-sen University · CN

Funding

national natural science foundation of china 81521001National Natural Science Foundation of China 82170258the basic research project of shanghai committee of science and technology 19JC1411400the laboratory animal science foundation of shanghai committee of science and technology 19140902000the laboratory animal science foundation of shanghai committee of science and technology 201409005000the national key research and development plan 2016YFC1101102
6 · The paper itself

Abstract

Myocardial infarction (MI) is a significant contributor to the development of heart failure. Histidine decarboxylase (HDC), the unique enzyme that converts L-histidine to histamine, is highly expressed in CD11b

Indexed as

HistamineHistidine DecarboxylaseMyeloid CellsMyocardial InfarctionMyofibroblastsAnimalsFibrosisMiceHistamineHistidine DecarboxylaseCardiac fibrosisHistidine decarboxylaseKrüppel-like factor 5MacrophageMyofibroblast transformation

Identifiers

PMID34734351
OpenAlexW3209257100

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.