ArticleIEEE open journal of engineering in medicine and biology2021
Untargeted Large Volume Hyperthermia Reduces Tumor Drug Uptake From Thermosensitive Liposomes.
Article in IEEE open journal of engineering in medicine and biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Exploiting the dynamics of hyperthermia-enhanced delivery of thermosensitive liposomal doxorubicin to solid tumors.Drug delivery · 2026Article
- A Comprehensive Review of Smart Thermosensitive Nanocarriers for Precision Cancer Therapy.International journal of molecular sciences · 2025Review
- Review
- Selecting ideal drugs for encapsulation in thermosensitive liposomes and other triggered nanoparticles.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2022Article
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Authors and funding
7 authors.
Funding
Abstract
goalThe impact of hyperthermia (HT) method on tumor drug uptake with thermosensitive liposomes (TSL) is not well understood.
methodsWe created realistic three-dimensional (3-D) computer models that simulate TSL-encapsulated doxorubicin (TSL-DOX) delivery in mouse tumors with three HT methods (thermistor probe (T), laser (L) and water bath (WB), at 15 min and 60 min HT duration), with corroborating
resultsAverage computer model-predicted tumor drug concentrations (
conclusionsUntargeted large volume HT causes poor tumor drug uptake from TSL.
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