Evidence map›Paper›PMID 34734186›Full record

ArticleFEMS microbes2021

Aaron M T Barnes, Kristi L Frank, Jennifer L Dale, Dawn A Manias, Jennifer L Powers, Gary M Dunny

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in FEMS microbes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Insights into ecology, pathogenesis, and biofilm formation ofMicrobiology and molecular biology reviews : MMBR · 2025
    Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Enterococcal Endocarditis: Hiding in Plain Sight.Frontiers in cellular and infection microbiology · 2021
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Aaron M T BarnesDepartment of Microbiology and Immunology, University of Minnesota School of Medicine, Minneapolis, MN 55455, USA.ORCID https://orcid.org/0000-0002-7014-7556
Kristi L FrankDepartment of Microbiology and Immunology, University of Minnesota School of Medicine, Minneapolis, MN 55455, USA.ORCID https://orcid.org/0000-0003-0050-3380
Jennifer L DaleDepartment of Microbiology and Immunology, University of Minnesota School of Medicine, Minneapolis, MN 55455, USA.
Dawn A ManiasDepartment of Microbiology and Immunology, University of Minnesota School of Medicine, Minneapolis, MN 55455, USA.
Jennifer L PowersDepartment of Microbiology and Immunology, University of Minnesota School of Medicine, Minneapolis, MN 55455, USA.
Gary M DunnyDepartment of Microbiology and Immunology, University of Minnesota School of Medicine, Minneapolis, MN 55455, USA.
University of Minnesota · US

Funding

Infectious Disease Training in Clinical InvestigationT32AI055433 · NIAID · UNIVERSITY OF MINNESOTA TWIN CITIES · PI David R Boulware · 2003 to 2026
$6.1M
Role of the enterococcal site 2 protease in biofilm formation, adaptation, and host-pathogen interactionsR01AI141961 · NIAID · HENRY M. JACKSON FDN FOR THE ADV MIL/MED · PI FRANK, KRISTI L · 2019 to 2023
$1.9M
NIAID NIH HHS R01 AI141961NIAID NIH HHS T32 AI055433
6 · The paper itself

Abstract

Infectious endocarditis (IE) is an uncommon disease with significant morbidity and mortality. The pathogenesis of IE has historically been described as a cascade of host-specific events beginning with endothelial damage and thrombus formation and followed by bacterial colonization of the nascent thrombus.

Indexed as

animal modelsbiofilmselectron microscopyendocarditisEnterococcus faecalismicrobiome

Identifiers

PMID34734186
PMCPMC8557322
OpenAlexW3202766321

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.