Evidence map›Paper›PMID 34734051›Full record

ArticleWorld journal of clinical cases2021

Development of a random forest model for hypotension prediction after anesthesia induction for cardiac surgery.

Xuan-Fa Li, Yong-Zhen Huang, Jing-Ying Tang, Rui-Chen Li, Xiao-Qi Wang

Open access · diamondAbstract read
In one paragraph

Article in World journal of clinical cases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Pooled it
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  3. Pooled it
  4. Review
  5. Article
  6. Article
  7. Article
  8. Risk factors for intraoperative hypotension during cardiac surgery.Indian journal of thoracic and cardiovascular surgery · 2025
    Article
  9. Article
  10. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Xuan-Fa LiDepartment of Anesthesiology, The Second Affiliated Hospital of Hainan Medical University, Haikou 570311, Hainan Province, China.
Yong-Zhen HuangDepartment of Anesthesiology, Hainan Hospital of Traditional Chinese Medicine, Haikou 570203, Hainan Province, China.
Jing-Ying TangDepartment of Anesthesiology, Hainan Provincial People's Hospital, Haikou 570000, Hainan Province, China.
Rui-Chen LiDepartment of Anesthesiology, The Second Affiliated Hospital of Hainan Medical University, Haikou 570311, Hainan Province, China.
Xiao-Qi WangDepartment of Anesthesiology, The Second Affiliated Hospital of Hainan Medical University, Haikou 570311, Hainan Province, China. wxq201904@163.com.
Hainan Medical University · CNHainan General Hospital · CNHainan Provincial Hospital of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHypotension after the induction of anesthesia is known to be associated with various adverse events. The involvement of a series of factors makes the prediction of hypotension during anesthesia quite challenging.

aimTo explore the ability and effectiveness of a random forest (RF) model in the prediction of post-induction hypotension (PIH) in patients undergoing cardiac surgery.

methodsPatient information was obtained from the electronic health records of the Second Affiliated Hospital of Hainan Medical University. The study included patients, ≥ 18 years of age, who underwent cardiac surgery from December 2007 to January 2018. An RF algorithm, which is a supervised machine learning technique, was employed to predict PIH. Model performance was assessed by the area under the curve (AUC) of the receiver operating characteristic. Mean decrease in the Gini index was used to rank various features based on their importance.

resultsOf the 3030 patients included in the study, 1578 (52.1%) experienced hypotension after the induction of anesthesia. The RF model performed effectively, with an AUC of 0.843 (0.808-0.877) and identified mean blood pressure as the most important predictor of PIH after anesthesia. Age and body mass index also had a significant impact.

conclusionThe generated RF model had high discrimination ability for the identification of individuals at high risk for a hypotensive event during cardiac surgery. The study results highlighted that machine learning tools confer unique advantages for the prediction of adverse post-anesthesia events.

Indexed as

AnesthesiaCardiac surgeryHypotension predictionMachine learningRandom forest

Identifiers

PMID34734051
PMCPMC8546817
OpenAlexW3205569974

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.