ArticleAnnals of translational medicine2021
Preoperative serum albumin: a promising indicator of early mortality after surgery for infective endocarditis.
Article in Annals of translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Comparison of the Predictive Value of CRP/Albumin, CRP/Prealbumin, and the Clinical Frailty Scale for Mortality in Geriatric Intensive Care Patients.Saudi medical journal · 2026Article
- Development and validation of a machine learning model for predicting 6-month mortality in patients with infective endocarditis.Biomedical engineering online · 2026Article
- Geriatric nutritional risk index improves risk scoring for mortality after TAVR compared to established scores.Frontiers in cardiovascular medicine · 2026Article
- Unveiling the Future of Infective Endocarditis Diagnosis: The Transformative Role of Metagenomic Next-Generation Sequencing in Culture-Negative Cases.Journal of epidemiology and global health · 2025Review
- Hypoalbuminemia and Postoperative Outcomes Following Major Salivary Gland Resection.Laryngoscope investigative otolaryngology · 2025Article
- Pathogenic spectrum of infective endocarditis and analysis of prognostic risk factors following surgical treatment in a tertiary hospital in China.BMC infectious diseases · 2024Article
- Evaluation of parameters predicting in-hospital mortality and septic embolisms in patients with infective endocarditis.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2024Article
- Clinical value of the red blood cell distribution width to albumin ratio in the assessment of prognosis in critically ill patients with sepsis: a retrospective analysis.Journal of thoracic disease · 2024Article
- Risk factors for mortality in surgical patients on combined continuous renal replacement therapy and extracorporeal membrane oxygenation: single-center retrospective study.Renal failure · 2023Article
- Machine Learning-Based Risk Model for Predicting Early Mortality After Surgery for Infective Endocarditis.Journal of the American Heart Association · 2022Article
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15 authors.
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Abstract
backgroundDespite novel improvements in the diagnosis and treatment of infective endocarditis (IE), there has been no significant improvement in the survival rate of IE, which indicates that many details still need to be optimized in the preoperative assessment. We sought to evaluate preoperative serum albumin as a biomarker for predicting early mortality after IE surgery.
methodsBetween October 2013 and June 2019, patients with a definite diagnosis of IE were enrolled in this study. Patients' albumin levels at admission were used as the preoperative albumin levels. Restricted cubic spline and multivariate logistic regression analyses were performed to evaluate the relationship between albumin and early mortality. Receiver operating characteristic curve analyses were performed to assess the role of albumin in predicting early mortality and compare the predictive capacity of traditional models with models that included albumin.
resultsOf the 276 IE patients, 20 (7.2%) died in hospital or within 30 days of surgery. Hypoalbuminemia (an albumin level <3.5 g/dL) was present in 109 (39.5%) patients. The multivariate logistic regression analysis showed that preoperative albumin was inversely associated with early mortality [adjusted odds ratio (OR) =0.22 per 1 g/dL, 95% confidence interval (CI): 0.07-0.65, P=0.006] after full adjustment. Preoperative albumin had value in predicting early mortality [area under the curve (AUC) =0.72, 95% CI: 0.61-0.84; P<0.01]. After adding albumin to the European System for Cardiac Operative Risk Evaluation (EuroSCORE) and Charlson score, the predictive ability of the model was further improved (EuroSCORE II: AUC =0.55; 95% CI: 0.42-0.67 to AUC =0.72; 95% CI: 0.61-0.84; Charlson score: AUC =0.73; 95% CI: 0.64-0.83 to AUC =0.78; 95% CI: 0.68-0.88).
conclusionsPreoperative serum albumin is inversely associated with early mortality after IE surgery, and is a promising prognostic indicator in preoperative risk stratification assessments of IE patients.
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