Evidence map›Paper›PMID 34733973›Full record

ArticleAnnals of translational medicine2021

3D-printed personalised prostheses for bone defect repair and reconstruction following resection of metacarpal giant cell tumours.

Lin Xu, Hao Qin, Zhilin Cheng, Wen-Bo Jiang, Jia Tan, Xiang Luo, Wenhua Huang

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Annals of translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07337018 (Valutazione Resezioni Oncologiche e Ricostruzione Con Utilizzo di Impianti Protesici in Chirurgia Oncologica Ortopedica), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07337018 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Valutazione Resezioni Oncologiche e Ricostruzione Con Utilizzo di Impianti Protesici in Chirurgia Oncologica Ortopedica (Evaluation of Oncologic Resections and Reconstruction Using Prosthetic Implants in Orthopedic Oncologic Surgery)

TypeobservationalSponsorFondazione Policlinico Universitario Agostino Gemelli IRCCSRan2026 to 2028Enrolled100ConditionsBone Tumor
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. 3D Bioprinting in Limb Salvage Surgery.Journal of functional biomaterials · 2024
    Review
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Lin XuDepartment of Human Anatomy, School of Basic Medical Sciences, Guangxi Medical University, Nanning, China.
Hao QinGuangxi Clinical Research Center for Digital Medicine and 3D Printing (Guigang City People's Hospital), Guigang, China.
Zhilin ChengGuangxi Clinical Research Center for Digital Medicine and 3D Printing (Guigang City People's Hospital), Guigang, China.
Wen-Bo JiangClinical and Translational Research Center for 3D Printing Technology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jia TanClinical and Translational Research Center for 3D Printing Technology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xiang LuoGuangxi Clinical Research Center for Digital Medicine and 3D Printing (Guigang City People's Hospital), Guigang, China.
Wenhua HuangDepartment of Human Anatomy, School of Basic Medical Sciences, Guangxi Medical University, Nanning, China.
Guigang City People's Hospital · CNGuangxi Medical University · CNShanghai Jiao Tong University · CNShanghai Ninth People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundConventional surgical treatment for metacarpal giant cell tumours (GCTs) includes lesion scraping followed by bone grafting or bone cement filling and

methodsThree patients with metacarpal GCTs were examined in a retrospective cohort study. Through preoperative planning, a 3D-printed personalised prosthesis was designed and created for bone defect repair and reconstruction after tumour resection. Prosthesis fit, limb function, pain on the affected side, and the occurrence of complications were evaluated postoperatively.

resultsPostoperative X-ray examination revealed a satisfactory fit of the 3D-printed prosthesis in terms of bone defect size and overall metacarpal shape, as well as good transverse and longitudinal metacarpal arches. The patients also exhibited good function in the affected limb, with good flexion and extension functions in the carpal, metacarpophalangeal, and interphalangeal joints, plus the absence of obvious pain, tumour recurrence, and complications such as pathologic fractures and prosthetic loosening.

conclusionsWhen using a 3D-printed personalised prosthesis for bone defect repair and reconstruction following resection of metacarpal GCTs, a good fit with the bone defect can be achieved during prosthetic installation when preoperative planning and design have been adequately performed. Therefore, three-dimensionally printed personalised prostheses can serve as an effective method for the treatment of metacarpal GCTs.

Indexed as

3D printinggiant cell tumour (GCT)metacarpalspersonalised prosthesis

Identifiers

PMID34733973
PMCPMC8506718
OpenAlexW3196843815

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.