Evidence map›Paper›PMID 34733915›Full record

ArticleAnnals of translational medicine2021

Effect of stroke screening survey on intravenous thrombolysis and long-term outcomes in acute ischemic stroke patients: the real-world evidence from Shanghai, China.

Fen Li, Yuqian Chen, Lan Hong, Bifan Zhu, Duo Chen, Xinyu Qin, Guangfeng Gao, Jianhua Xu, Xin Cheng, Qiang Dong and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Annals of translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Fen LiDepartment of Health Policy Research, Shanghai Health Development Research Center, Shanghai, China.
Yuqian ChenDepartment of Health Policy Research, Shanghai Health Development Research Center, Shanghai, China.
Lan HongDepartment of Neurology, Huashan Hospital Affiliated to Fudan University, Shanghai, China.
Bifan ZhuDepartment of Health Policy Research, Shanghai Health Development Research Center, Shanghai, China.
Duo ChenDepartment of Health Policy Research, Shanghai Health Development Research Center, Shanghai, China.
Xinyu QinDepartment of Health Policy Research, Shanghai Health Development Research Center, Shanghai, China.
Guangfeng GaoJiading Information Center for Health, Shanghai, China.
Jianhua XuDepartment of Neurology, Jiading Central Hospital Affiliated to Shanghai University of Medicine and Health Science, Shanghai, China.
Xin ChengDepartment of Neurology, Huashan Hospital Affiliated to Fudan University, Shanghai, China.
Qiang DongDepartment of Neurology, Huashan Hospital Affiliated to Fudan University, Shanghai, China.
Chunlin JinDepartment of Health Policy Research, Shanghai Health Development Research Center, Shanghai, China.
Kun FangDepartment of Neurology, Huashan Hospital Affiliated to Fudan University, Shanghai, China.
Development Research Center · CNFudan University · CNJiading District Central Hospital · CNShanghai Medical Information Center · CNHuashan Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe stroke screening survey (SSS) is an essential strategy for stroke prevention. However, previous studies rarely discussed the effect of SSS on the acute phase treatment procedure for acute ischemic stroke (AIS) and the long-term prognosis outcomes. This study aims to investigate the effect of SSS on intravenous thrombolysis and long-term outcomes in AIS patients.

methodsThe stroke patients included were collected from Jiading Residences Community Health Records and Shanghai Stroke Service System database, from January 2017 to December 2019. Patients were divided into two groups, according to whether they have been screened before the event (onset and death). Demographic characteristics and treatment information of patients in the two groups were compared by the Mann-Whitney test and Chi-square test. The demographic differences between groups were adjusted with Propensity Score Matching (PSM) to evaluate the effect of SSS on door-to-needle time (DNT). The Kaplan-Meier survival curve with a log-rank test and multiple Cox regression model were used to evaluate the effect of SSS on long-term lifetime.

resultsA total of 1,236 patients with AIS were collected, including 468 (37.86%) female, 126 (10.19%) patients with intravenous thrombolysis, 241 (23.30%) patients died from all-cause mortality by January 8, 2020. A total of 124 (10.03%) patients have been screened before AIS onset, and 261 (21.17%) patients had undergone SSS after AIS onset. The baseline information indicated that patients with previous screening were older than the patients without at the time of onset [75 (70, 83)

conclusionsFor AIS patients, the SSS is associated with less severe onset situation, shorter DNT, and longer long-term lifetime.

Indexed as

Acute ischemic stroke (AIS)door-to-needle time (DNT)intravenous thrombolysisstroke screening survey (SSS)survival analysis

Identifiers

PMID34733915
PMCPMC8506527
OpenAlexW3194827216

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.